A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine

A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine

Ketamine, a non-competitive N-methyl-D-aspartate receptor (NMDAR) antagonist, has received much attention for its rapid antidepressant effects. A single administration of ketamine elicits rapid and sustained antidepressant effects in both humans and animals. Current efforts are focused on uncovering...

Full description

Bibliographic Details
Main Authors: Ola Sobhy A. Elmeseiny, Heidi Kaastrup Müller
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Pharmacological Research
Subjects:
mGluR5
Ketamine
Homer1a
Antidepressant
Molecular mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824000252

Similar Items

Similar Items