A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine

A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine

Ketamine, a non-competitive N-methyl-D-aspartate receptor (NMDAR) antagonist, has received much attention for its rapid antidepressant effects. A single administration of ketamine elicits rapid and sustained antidepressant effects in both humans and animals. Current efforts are focused on uncovering...

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Manylion Llyfryddiaeth
Prif Awduron: Ola Sobhy A. Elmeseiny, Heidi Kaastrup Müller
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Elsevier 2024-02-01
Cyfres:Pharmacological Research
Pynciau:
mGluR5
Ketamine
Homer1a
Antidepressant
Molecular mechanism
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S1043661824000252

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http://www.sciencedirect.com/science/article/pii/S1043661824000252

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