Orchitis: An unusual presentation of polyarteritis nodosa

Polyarteritis nodosa (PAN), a systemic necrotizing vasculitis with multiorgan development, is generally restricted to the medium-sized muscular arteries. The varied initial clinical presentations of PAN can lead to a delayed diagnosis. We present the case of a middle-aged male patient who presented...

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Main Authors: Nelofar Islam, Debanjali Sinha, Parasar Ghosh, Chhanda Datta, Uttara Chatterjee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=4;spage=600;epage=603;aulast=Islam
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author Nelofar Islam
Debanjali Sinha
Parasar Ghosh
Chhanda Datta
Uttara Chatterjee
author_facet Nelofar Islam
Debanjali Sinha
Parasar Ghosh
Chhanda Datta
Uttara Chatterjee
author_sort Nelofar Islam
collection DOAJ
description Polyarteritis nodosa (PAN), a systemic necrotizing vasculitis with multiorgan development, is generally restricted to the medium-sized muscular arteries. The varied initial clinical presentations of PAN can lead to a delayed diagnosis. We present the case of a middle-aged male patient who presented with an acute onset right-sided testicular pain as the initial clinical symptom with ischemic changes on ultrasonogram, thereby requiring orchiectomy. This was reported to be a case of tubercular epididymo-orchitis. On review, the biopsy revealed features of necrotizing arteritis as seen in PAN with fibrinoid necrosis and giant cells, thus highlighting the fact that vasculitis due to PAN may have a localized presentation at the time of diagnosis. PAN should be distinguished from other causes of epididymo-orchitis and other vasculitis lesions, the most common being tubercular etiology in the Asian population.
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spelling doaj.art-7ca81ab09ea7434eb1a5b34fa149bbdb2022-12-21T18:56:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292018-01-0161460060310.4103/IJPM.IJPM_569_17Orchitis: An unusual presentation of polyarteritis nodosaNelofar IslamDebanjali SinhaParasar GhoshChhanda DattaUttara ChatterjeePolyarteritis nodosa (PAN), a systemic necrotizing vasculitis with multiorgan development, is generally restricted to the medium-sized muscular arteries. The varied initial clinical presentations of PAN can lead to a delayed diagnosis. We present the case of a middle-aged male patient who presented with an acute onset right-sided testicular pain as the initial clinical symptom with ischemic changes on ultrasonogram, thereby requiring orchiectomy. This was reported to be a case of tubercular epididymo-orchitis. On review, the biopsy revealed features of necrotizing arteritis as seen in PAN with fibrinoid necrosis and giant cells, thus highlighting the fact that vasculitis due to PAN may have a localized presentation at the time of diagnosis. PAN should be distinguished from other causes of epididymo-orchitis and other vasculitis lesions, the most common being tubercular etiology in the Asian population.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=4;spage=600;epage=603;aulast=IslamEpididymo-orchitispolyarteritis nodosavasculitis
spellingShingle Nelofar Islam
Debanjali Sinha
Parasar Ghosh
Chhanda Datta
Uttara Chatterjee
Orchitis: An unusual presentation of polyarteritis nodosa
Indian Journal of Pathology and Microbiology
Epididymo-orchitis
polyarteritis nodosa
vasculitis
title Orchitis: An unusual presentation of polyarteritis nodosa
title_full Orchitis: An unusual presentation of polyarteritis nodosa
title_fullStr Orchitis: An unusual presentation of polyarteritis nodosa
title_full_unstemmed Orchitis: An unusual presentation of polyarteritis nodosa
title_short Orchitis: An unusual presentation of polyarteritis nodosa
title_sort orchitis an unusual presentation of polyarteritis nodosa
topic Epididymo-orchitis
polyarteritis nodosa
vasculitis
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=4;spage=600;epage=603;aulast=Islam
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AT debanjalisinha orchitisanunusualpresentationofpolyarteritisnodosa
AT parasarghosh orchitisanunusualpresentationofpolyarteritisnodosa
AT chhandadatta orchitisanunusualpresentationofpolyarteritisnodosa
AT uttarachatterjee orchitisanunusualpresentationofpolyarteritisnodosa