Orchitis: An unusual presentation of polyarteritis nodosa
Polyarteritis nodosa (PAN), a systemic necrotizing vasculitis with multiorgan development, is generally restricted to the medium-sized muscular arteries. The varied initial clinical presentations of PAN can lead to a delayed diagnosis. We present the case of a middle-aged male patient who presented...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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Series: | Indian Journal of Pathology and Microbiology |
Subjects: | |
Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=4;spage=600;epage=603;aulast=Islam |
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author | Nelofar Islam Debanjali Sinha Parasar Ghosh Chhanda Datta Uttara Chatterjee |
author_facet | Nelofar Islam Debanjali Sinha Parasar Ghosh Chhanda Datta Uttara Chatterjee |
author_sort | Nelofar Islam |
collection | DOAJ |
description | Polyarteritis nodosa (PAN), a systemic necrotizing vasculitis with multiorgan development, is generally restricted to the medium-sized muscular arteries. The varied initial clinical presentations of PAN can lead to a delayed diagnosis. We present the case of a middle-aged male patient who presented with an acute onset right-sided testicular pain as the initial clinical symptom with ischemic changes on ultrasonogram, thereby requiring orchiectomy. This was reported to be a case of tubercular epididymo-orchitis. On review, the biopsy revealed features of necrotizing arteritis as seen in PAN with fibrinoid necrosis and giant cells, thus highlighting the fact that vasculitis due to PAN may have a localized presentation at the time of diagnosis. PAN should be distinguished from other causes of epididymo-orchitis and other vasculitis lesions, the most common being tubercular etiology in the Asian population. |
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format | Article |
id | doaj.art-7ca81ab09ea7434eb1a5b34fa149bbdb |
institution | Directory Open Access Journal |
issn | 0377-4929 |
language | English |
last_indexed | 2024-12-21T16:59:26Z |
publishDate | 2018-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Pathology and Microbiology |
spelling | doaj.art-7ca81ab09ea7434eb1a5b34fa149bbdb2022-12-21T18:56:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292018-01-0161460060310.4103/IJPM.IJPM_569_17Orchitis: An unusual presentation of polyarteritis nodosaNelofar IslamDebanjali SinhaParasar GhoshChhanda DattaUttara ChatterjeePolyarteritis nodosa (PAN), a systemic necrotizing vasculitis with multiorgan development, is generally restricted to the medium-sized muscular arteries. The varied initial clinical presentations of PAN can lead to a delayed diagnosis. We present the case of a middle-aged male patient who presented with an acute onset right-sided testicular pain as the initial clinical symptom with ischemic changes on ultrasonogram, thereby requiring orchiectomy. This was reported to be a case of tubercular epididymo-orchitis. On review, the biopsy revealed features of necrotizing arteritis as seen in PAN with fibrinoid necrosis and giant cells, thus highlighting the fact that vasculitis due to PAN may have a localized presentation at the time of diagnosis. PAN should be distinguished from other causes of epididymo-orchitis and other vasculitis lesions, the most common being tubercular etiology in the Asian population.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=4;spage=600;epage=603;aulast=IslamEpididymo-orchitispolyarteritis nodosavasculitis |
spellingShingle | Nelofar Islam Debanjali Sinha Parasar Ghosh Chhanda Datta Uttara Chatterjee Orchitis: An unusual presentation of polyarteritis nodosa Indian Journal of Pathology and Microbiology Epididymo-orchitis polyarteritis nodosa vasculitis |
title | Orchitis: An unusual presentation of polyarteritis nodosa |
title_full | Orchitis: An unusual presentation of polyarteritis nodosa |
title_fullStr | Orchitis: An unusual presentation of polyarteritis nodosa |
title_full_unstemmed | Orchitis: An unusual presentation of polyarteritis nodosa |
title_short | Orchitis: An unusual presentation of polyarteritis nodosa |
title_sort | orchitis an unusual presentation of polyarteritis nodosa |
topic | Epididymo-orchitis polyarteritis nodosa vasculitis |
url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=4;spage=600;epage=603;aulast=Islam |
work_keys_str_mv | AT nelofarislam orchitisanunusualpresentationofpolyarteritisnodosa AT debanjalisinha orchitisanunusualpresentationofpolyarteritisnodosa AT parasarghosh orchitisanunusualpresentationofpolyarteritisnodosa AT chhandadatta orchitisanunusualpresentationofpolyarteritisnodosa AT uttarachatterjee orchitisanunusualpresentationofpolyarteritisnodosa |