Degradation of Glycocalyx and Multiple Manifestations of Endothelial Dysfunction Coincide in the Early Phase of Endothelial Dysfunction Before Atherosclerotic Plaque Development in Apolipoprotein E/Low‐Density Lipoprotein Receptor‐Deficient Mice

Degradation of Glycocalyx and Multiple Manifestations of Endothelial Dysfunction Coincide in the Early Phase of Endothelial Dysfunction Before Atherosclerotic Plaque Development in Apolipoprotein E/Low‐Density Lipoprotein Receptor‐Deficient Mice

Background The impairment of endothelium‐dependent vasodilation, increased endothelial permeability, and glycocalyx degradation are all important pathophysiological components of endothelial dysfunction. However, it is still not clear whether in atherosclerosis, glycocalyx injury precedes other feat...

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Bibliographic Details
Main Authors: Anna Bar, Marta Targosz‐Korecka, Joanna Suraj, Bartosz Proniewski, Agnieszka Jasztal, Brygida Marczyk, Magdalena Sternak, Magdalena Przybyło, Anna Kurpińska, Maria Walczak, Renata B. Kostogrys, Marek Szymonski, Stefan Chlopicki
Format: Article
Language:English
Published: Wiley 2019-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
atomic force microscopy
endothelial function
glycocalyx
magnetic resonance imaging
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.011171

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