Single-cell expression profile of Drosophila ovarian follicle stem cells illuminates spatial differentiation in the germarium

Single-cell expression profile of Drosophila ovarian follicle stem cells illuminates spatial differentiation in the germarium

Abstract Background How stem cell populations are organized and regulated within adult tissues is important for understanding cancer origins and for developing cell replacement strategies. Paradigms such as mammalian gut stem cells and Drosophila ovarian follicle stem cells (FSC) are characterized b...

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Bibliographic Details
Main Authors: Zhi Dong, Lan Pang, Zhiguo Liu, Yifeng Sheng, Xiaoping Li, Xavier Thibault, Amy Reilein, Daniel Kalderon, Jianhua Huang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Biology
Subjects:
Drosophila
Adult stem cells
Follicle stem cells
Ovary
Single-cell RNA sequencing
Online Access:https://doi.org/10.1186/s12915-023-01636-9

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