GOMOZIGOTNAYa MUTATsIYa V GENE INGIBITORA AKTIVATORA PLAZMINOGENA 1 U PATsIENTOV S ANTIFOSFOLIPIDNYM SINDROMOM

GOMOZIGOTNAYa MUTATsIYa V GENE INGIBITORA AKTIVATORA PLAZMINOGENA 1 U PATsIENTOV S ANTIFOSFOLIPIDNYM SINDROMOM

Antifosfolipidnyi sindrom (AFS) – simptomo- kompleks, proyavlyayushchiisya trombozom sosudov razlichnoi lokalizatsii i kalibra pri obyazatel'nom nalichii v krovi antifosfolipidnykh antitel (aFL) [1]. K serologicheskim markeram AFS, soglasno mezhdunarodnym diagnosticheskim kriteriyam, otneseny:...

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Bibliographic Details
Main Authors: E. V. Ostryakova, N. L. Patrusheva, A. P. Aleksankin, L. I. Patrushev, N. V. Seredavkina, E. N. Aleksandrova, A. V. Volkov, T. M. Reshetnyak
Format: Article
Language:Russian
Published: IMA PRESS LLC 2011-06-01
Series:Научно-практическая ревматология
Online Access:https://rsp.mediar-press.net/rsp/article/view/1297
Description
Summary:Antifosfolipidnyi sindrom (AFS) – simptomo- kompleks, proyavlyayushchiisya trombozom sosudov razlichnoi lokalizatsii i kalibra pri obyazatel'nom nalichii v krovi antifosfolipidnykh antitel (aFL) [1]. K serologicheskim markeram AFS, soglasno mezhdunarodnym diagnosticheskim kriteriyam, otneseny: antitela k kardiolipinu (aKL) i/ili volchanochnyi antikoagulyant (VA), i/ili antitela k β2-glikoproteinu 1 (anti-β2-GP 1). V zavisimosti ot pozitivnosti po aFL rekomendovano stratifitsirovat' bol'nykh AFS po sleduyushchim kategoriyam: I – vyyavlenie bolee odnogo laboratornogo markera (v lyuboi kombinatsii); IIa – tol'ko VA; IIb – tol'ko aKL; IIc – tol'ko anti-β2-GP 1 [2]
ISSN:1995-4484
1995-4492

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