CD27+ microparticle interactions and immunoregulation of CD4+ T lymphocytes

CD27+ microparticle interactions and immunoregulation of CD4+ T lymphocytes

IntroductionAplasia and hematological malignancies are treated with platelet transfusions, which can have major immunomodulatory effects. Platelet concentrates (PCs) contain many immunomodulatory elements, including the platelets themselves, residual leukocytes, extracellular vesicles, such as micro...

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Bibliographic Details
Main Authors: Léonie Cagnet, Déborah Neyrinck-Leglantier, Marie Tamagne, Lylia Berradhia, Mehdi Khelfa, Sabine Cleophax, France Pirenne, Benoît Vingert
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
microparticles
CD27/CD70
CD4+ TLs
immunomodulation
platelet concentrate
transfusion
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1043255/full

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