New onset asthma during pregnancy: two case reports [version 2; peer review: 2 approved]
Introduction: Asthma is the most common chronic respiratory disease during pregnancy. However, reports of new onset asthma during pregnancy are lacking. We report two cases of new onset asthma during pregnancy following respiratory tract infection, subsequently one case with M. pneumoniae infection...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2023-03-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/10-1120/v2 |
| _version_ | 1797852253113024512 |
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| author | Jeroen van Exsel Paula S. Schriek Saar A. Bendien Hanneke A. Feitsma |
| author_facet | Jeroen van Exsel Paula S. Schriek Saar A. Bendien Hanneke A. Feitsma |
| author_sort | Jeroen van Exsel |
| collection | DOAJ |
| description | Introduction: Asthma is the most common chronic respiratory disease during pregnancy. However, reports of new onset asthma during pregnancy are lacking. We report two cases of new onset asthma during pregnancy following respiratory tract infection, subsequently one case with M. pneumoniae infection and the other case with a combined infection with respiratory syncytial virus and rhinovirus. Case presentation: Both patients presented with the clinical features of an acute asthma exacerbation during pregnancy without a medical history of asthma. During follow up the diagnosis of asthma was supported by spirometry showing significant reversibility and elevated fractional exhaled nitric oxide (FeNO). Patients were hospitalized and received supplemental oxygen, treatment for an acute asthma exacerbation with systemic corticosteroids, high dose inhalation therapy. These therapeutic interventions subsequently led to a good outcome for the mother and newborn in both cases. Conclusions: New onset asthma should be part of the differential diagnosis in pregnant patients with respiratory symptoms, particularly in case of mycoplasma infection. Diagnosing asthma during pregnancy can be challenging. In these circumstances, additional diagnostic tests (like inflammatory biomarkers FeNO and blood eosinophils) can be helpful to support the diagnosis. |
| first_indexed | 2024-04-09T19:31:04Z |
| format | Article |
| id | doaj.art-7cbd432e8d3d45baa582e1f55465fe5d |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-04-09T19:31:04Z |
| publishDate | 2023-03-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-7cbd432e8d3d45baa582e1f55465fe5d2023-04-05T00:00:00ZengF1000 Research LtdF1000Research2046-14022023-03-0110144449New onset asthma during pregnancy: two case reports [version 2; peer review: 2 approved]Jeroen van Exsel0Paula S. Schriek1https://orcid.org/0000-0003-0210-8712Saar A. Bendien2Hanneke A. Feitsma3Department of Respiratory Medicine, Haga Teaching Hospital, The Hague, South Holland, 2545AA, The NetherlandsDepartment of Respiratory Medicine, Haga Teaching Hospital, The Hague, South Holland, 2545AA, The NetherlandsDepartment of Respiratory Medicine, Haga Teaching Hospital, The Hague, South Holland, 2545AA, The NetherlandsDepartment of gynaecology, Haga Teaching Hospital, The Hague, South Holland, 2545AA, The NetherlandsIntroduction: Asthma is the most common chronic respiratory disease during pregnancy. However, reports of new onset asthma during pregnancy are lacking. We report two cases of new onset asthma during pregnancy following respiratory tract infection, subsequently one case with M. pneumoniae infection and the other case with a combined infection with respiratory syncytial virus and rhinovirus. Case presentation: Both patients presented with the clinical features of an acute asthma exacerbation during pregnancy without a medical history of asthma. During follow up the diagnosis of asthma was supported by spirometry showing significant reversibility and elevated fractional exhaled nitric oxide (FeNO). Patients were hospitalized and received supplemental oxygen, treatment for an acute asthma exacerbation with systemic corticosteroids, high dose inhalation therapy. These therapeutic interventions subsequently led to a good outcome for the mother and newborn in both cases. Conclusions: New onset asthma should be part of the differential diagnosis in pregnant patients with respiratory symptoms, particularly in case of mycoplasma infection. Diagnosing asthma during pregnancy can be challenging. In these circumstances, additional diagnostic tests (like inflammatory biomarkers FeNO and blood eosinophils) can be helpful to support the diagnosis.https://f1000research.com/articles/10-1120/v2asthma pregnancy infection exacerbationeng |
| spellingShingle | Jeroen van Exsel Paula S. Schriek Saar A. Bendien Hanneke A. Feitsma New onset asthma during pregnancy: two case reports [version 2; peer review: 2 approved] F1000Research asthma pregnancy infection exacerbation eng |
| title | New onset asthma during pregnancy: two case reports [version 2; peer review: 2 approved] |
| title_full | New onset asthma during pregnancy: two case reports [version 2; peer review: 2 approved] |
| title_fullStr | New onset asthma during pregnancy: two case reports [version 2; peer review: 2 approved] |
| title_full_unstemmed | New onset asthma during pregnancy: two case reports [version 2; peer review: 2 approved] |
| title_short | New onset asthma during pregnancy: two case reports [version 2; peer review: 2 approved] |
| title_sort | new onset asthma during pregnancy two case reports version 2 peer review 2 approved |
| topic | asthma pregnancy infection exacerbation eng |
| url | https://f1000research.com/articles/10-1120/v2 |
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