Role of Receptor Tyrosine Kinases and Their Ligands in Glioblastoma

Role of Receptor Tyrosine Kinases and Their Ligands in Glioblastoma

Glioblastoma multiforme is the most frequent, aggressive and fatal type of brain tumor. Glioblastomas are characterized by their infiltrating nature, high proliferation rate and resistance to chemotherapy and radiation. Recently, oncologic therapy experienced a rapid evolution towards “targeted ther...

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Bibliographic Details
Main Authors: Estefanía Carrasco-García, Miguel Saceda, Isabel Martínez-Lacaci
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Cells
Subjects:
RTK
EGFR
PDGFR
IGF-1R
glioblastoma multiforme
Online Access:http://www.mdpi.com/2073-4409/3/2/199

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