Radiation Damage in Carnidazole: a Single Crystal EPR Study
Single crystals of hydrated and anhydrous carnidazole have been subjected to X-irradiation at 77 K and studied by EPR. The determination of the EPR tensors shows that NO2, sulfur-centered radicals as well as a radical pair can be generated from this molecule; it appears that the species tr...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
1992-04-01
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| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/2113 |
| Summary: | Single crystals of hydrated and anhydrous carnidazole have been subjected to X-irradiation at 77 K and studied by EPR. The determination of the EPR tensors shows that NO2, sulfur-centered radicals as well as a radical pair can be generated from this molecule; it appears that
the species trapped at 77 K are not the same in the hydrated and in the anhydrous crystal. The results are discussed in the context of the radiosensitizing action of molecules containing a 5-nitroimidazole moiety.
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| ISSN: | 0009-4293 2673-2424 |