Radiation Damage in Carnidazole: a Single Crystal EPR Study
Single crystals of hydrated and anhydrous carnidazole have been subjected to X-irradiation at 77 K and studied by EPR. The determination of the EPR tensors shows that NO2, sulfur-centered radicals as well as a radical pair can be generated from this molecule; it appears that the species tr...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
1992-04-01
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| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/2113 |
| _version_ | 1818294388873232384 |
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| author | Théo Berclaz Gérald Bernardinelli Michel Geoffroy Natarajan Rajalakshmi |
| author_facet | Théo Berclaz Gérald Bernardinelli Michel Geoffroy Natarajan Rajalakshmi |
| author_sort | Théo Berclaz |
| collection | DOAJ |
| description |
Single crystals of hydrated and anhydrous carnidazole have been subjected to X-irradiation at 77 K and studied by EPR. The determination of the EPR tensors shows that NO2, sulfur-centered radicals as well as a radical pair can be generated from this molecule; it appears that
the species trapped at 77 K are not the same in the hydrated and in the anhydrous crystal. The results are discussed in the context of the radiosensitizing action of molecules containing a 5-nitroimidazole moiety.
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| first_indexed | 2024-12-13T03:30:58Z |
| format | Article |
| id | doaj.art-7cc785a35ff94d939b54ad3ddc9cf83f |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-12-13T03:30:58Z |
| publishDate | 1992-04-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-7cc785a35ff94d939b54ad3ddc9cf83f2022-12-22T00:01:10ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241992-04-01464Radiation Damage in Carnidazole: a Single Crystal EPR StudyThéo BerclazGérald BernardinelliMichel GeoffroyNatarajan Rajalakshmi Single crystals of hydrated and anhydrous carnidazole have been subjected to X-irradiation at 77 K and studied by EPR. The determination of the EPR tensors shows that NO2, sulfur-centered radicals as well as a radical pair can be generated from this molecule; it appears that the species trapped at 77 K are not the same in the hydrated and in the anhydrous crystal. The results are discussed in the context of the radiosensitizing action of molecules containing a 5-nitroimidazole moiety. https://www.chimia.ch/chimia/article/view/2113 |
| spellingShingle | Théo Berclaz Gérald Bernardinelli Michel Geoffroy Natarajan Rajalakshmi Radiation Damage in Carnidazole: a Single Crystal EPR Study CHIMIA |
| title | Radiation Damage in Carnidazole: a Single Crystal EPR Study |
| title_full | Radiation Damage in Carnidazole: a Single Crystal EPR Study |
| title_fullStr | Radiation Damage in Carnidazole: a Single Crystal EPR Study |
| title_full_unstemmed | Radiation Damage in Carnidazole: a Single Crystal EPR Study |
| title_short | Radiation Damage in Carnidazole: a Single Crystal EPR Study |
| title_sort | radiation damage in carnidazole a single crystal epr study |
| url | https://www.chimia.ch/chimia/article/view/2113 |
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