The Shigella flexneri virulence factor apyrase is released inside eukaryotic cells to hijack host cell fate

The Shigella flexneri virulence factor apyrase is released inside eukaryotic cells to hijack host cell fate

ABSTRACT Intestinal epithelial cells represent the first line of defense from invading enteric pathogens. During the course of infection, pro-inflammatory programmed cell death is an effective way to eliminate invading microbes and to create a localized inflammatory environment. On the other hand, p...

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Bibliographic Details
Main Authors: Lisa Perruzza, Carlo Zagaglia, Laura Vitiello, Meysam Sarshar, Francesco Strati, Martina Pasqua, Fabio Grassi, Mauro Nicoletti, Anna Teresa Palamara, Cecilia Ambrosi, Daniela Scribano
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
Shigella flexneri
apyrase
ATP
pyroptosis
inflammation
host cell survival
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00775-23

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