T regulatory cells metabolism: The influence on functional properties and treatment potential

T regulatory cells metabolism: The influence on functional properties and treatment potential

CD4+CD25highFoxP3+ regulatory T cells (Tregs) constitute a small but substantial fraction of lymphocytes in the immune system. Tregs control inflammation associated with infections but also when it is improperly directed against its tissues or cells. The ability of Tregs to suppress (inhibit) the im...

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Bibliographic Details
Main Authors: Martyna Tomaszewicz, Anna Ronowska, Maciej Zieliński, Agnieszka Jankowska-Kulawy, Piotr Trzonkowski
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
metabolism
autoimmunity
glycolysis
fatty acid oxidation
mTOR
ischemia
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1122063/full

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