Efficacy and Safety of Lomitapide in Homozygous Familial Hypercholesterolaemia: A Systematic Review

Efficacy and Safety of Lomitapide in Homozygous Familial Hypercholesterolaemia: A Systematic Review

Background: Homozygous familial hypercholesterolaemia (HoFH) patients have little or no low-density lipoprotein receptor (LDLR) function. HMG-CoA (3-hydroxy-3-methyl glutaryl coenzyme A) reductase inhibitors (statins) and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have limited...

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Bibliographic Details
Main Authors: Namin Wei, Yuanhui Hu, Siyu Li, Guoxiu Liu, Nang Zhang, Qiulei Jia, Jingjing Shi, Guozhen Yuan, Huaqiang Zhai
Format: Article
Language:English
Published: IMR Press 2022-04-01
Series:Reviews in Cardiovascular Medicine
Subjects:
homozygous familial hypercholesterolemia (hofh)
lomitapide
systematic review
efficacy
safety
Online Access:https://www.imrpress.com/journal/RCM/23/5/10.31083/j.rcm2305151

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https://www.imrpress.com/journal/RCM/23/5/10.31083/j.rcm2305151

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