Electrical responses and spontaneous activity of human iPS-derived neuronal networks characterized for three-month culture with 4096-electrode arrays

Electrical responses and spontaneous activity of human iPS-derived neuronal networks characterized for three-month culture with 4096-electrode arrays

The recent availability of human induced pluripotent stem cells (hiPSCs) holds great promise as a novel source of human-derived neurons for cell and tissue therapies as well as for in vitro drug screenings that might replace the use of animal models. However, there is still a considerable lack of kn...

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Bibliographic Details
Main Authors: Hayder eAmin, Alessandro eMaccione, Federica eMarinaro, Stefano eZordan, Thierry eNieus, Luca eBerdondini
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Neuroscience
Subjects:
neural networks
Surface functionalization
IPSC-derived neurons
spontaneous and evoked activities
CMOS-multielectrode arrays
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00121/full

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