Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention

Complex percutaneous coronary intervention (PCI) patients are a high-risk population for ischemic complications. Antiplatelet therapy in such patients remains controversial, as the beneficial effects of more potent agents use or prolonged dual antiplatelet treatment (DAPT) on atherothrombotic compli...

Full description

Bibliographic Details
Main Authors: Dimitrios Alexopoulos, Charalampos Varlamos, Despoina-Rafailia Benetou
Format: Article
Language:English
Published: Radcliffe Medical Media 2020-11-01
Series:US Cardiology Review
Online Access:https://www.uscjournal.com/articles/type-and-duration-of-dual-antiplatelet-therapy
_version_ 1797200055706320896
author Dimitrios Alexopoulos
Charalampos Varlamos
Despoina-Rafailia Benetou
author_facet Dimitrios Alexopoulos
Charalampos Varlamos
Despoina-Rafailia Benetou
author_sort Dimitrios Alexopoulos
collection DOAJ
description Complex percutaneous coronary intervention (PCI) patients are a high-risk population for ischemic complications. Antiplatelet therapy in such patients remains controversial, as the beneficial effects of more potent agents use or prolonged dual antiplatelet treatment (DAPT) on atherothrombotic complications are hindered by a concomitant increase in bleeding rates. The aim of this article is to describe ischemic and bleeding outcomes associated with complex PCI procedures and to compare different types and durations of DAPT regimens in terms of safety and efficacy outcomes. Issues concerning special patient groups, such as those with left main, chronic total occlusion, or bifurcation lesions, are discussed.
first_indexed 2024-03-07T17:41:00Z
format Article
id doaj.art-7cd2d99bafad4623b7befa5181ab0d7c
institution Directory Open Access Journal
issn 1758-3896
1758-390X
language English
last_indexed 2024-04-24T07:25:34Z
publishDate 2020-11-01
publisher Radcliffe Medical Media
record_format Article
series US Cardiology Review
spelling doaj.art-7cd2d99bafad4623b7befa5181ab0d7c2024-04-20T16:02:01ZengRadcliffe Medical MediaUS Cardiology Review1758-38961758-390X2020-11-011410.15420/usc.2020.13Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary InterventionDimitrios Alexopoulos0Charalampos Varlamos1Despoina-Rafailia Benetou2Second Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, GreeceSecond Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, GreeceSecond Department of Cardiology, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, GreeceComplex percutaneous coronary intervention (PCI) patients are a high-risk population for ischemic complications. Antiplatelet therapy in such patients remains controversial, as the beneficial effects of more potent agents use or prolonged dual antiplatelet treatment (DAPT) on atherothrombotic complications are hindered by a concomitant increase in bleeding rates. The aim of this article is to describe ischemic and bleeding outcomes associated with complex PCI procedures and to compare different types and durations of DAPT regimens in terms of safety and efficacy outcomes. Issues concerning special patient groups, such as those with left main, chronic total occlusion, or bifurcation lesions, are discussed.https://www.uscjournal.com/articles/type-and-duration-of-dual-antiplatelet-therapy
spellingShingle Dimitrios Alexopoulos
Charalampos Varlamos
Despoina-Rafailia Benetou
Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention
US Cardiology Review
title Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention
title_full Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention
title_fullStr Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention
title_full_unstemmed Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention
title_short Type and Duration of Dual Antiplatelet Therapy in Complex Percutaneous Coronary Intervention
title_sort type and duration of dual antiplatelet therapy in complex percutaneous coronary intervention
url https://www.uscjournal.com/articles/type-and-duration-of-dual-antiplatelet-therapy
work_keys_str_mv AT dimitriosalexopoulos typeanddurationofdualantiplatelettherapyincomplexpercutaneouscoronaryintervention
AT charalamposvarlamos typeanddurationofdualantiplatelettherapyincomplexpercutaneouscoronaryintervention
AT despoinarafailiabenetou typeanddurationofdualantiplatelettherapyincomplexpercutaneouscoronaryintervention