Physiology of the volume-sensitive/regulatory anion channel VSOR/VRAC. Part 1: from its discovery and phenotype characterization to the molecular entity identification

Physiology of the volume-sensitive/regulatory anion channel VSOR/VRAC. Part 1: from its discovery and phenotype characterization to the molecular entity identification

Abstract The volume-sensitive outwardly rectifying or volume-regulated anion channel, VSOR/VRAC, which was discovered in 1988, is expressed in most vertebrate cell types and is essentially involved in cell volume regulation after swelling and in the induction of cell death. This series of review art...

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Bibliographic Details
Main Author: Yasunobu Okada
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Physiological Sciences
Subjects:
Volume-sensitive anion channel
Regulatory volume decrease
Phenotypical properties
Molecular entities
LRRC8
TRPM7
Online Access:https://doi.org/10.1186/s12576-023-00897-x

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