An ATP and oxalate generating variant tricarboxylic acid cycle counters aluminum toxicity in Pseudomonas fluorescens.
Although the tricarboxylic acid (TCA) cycle is essential in almost all aerobic organisms, its precise modulation and integration in global cellular metabolism is not fully understood. Here, we report on an alternative TCA cycle uniquely aimed at generating ATP and oxalate, two metabolites critical f...
Main Authors: | Ranji Singh, Joseph Lemire, Ryan J Mailloux, Daniel Chénier, Robert Hamel, Vasu D Appanna |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2752808?pdf=render |
Similar Items
-
The tricarboxylic acid cycle, an ancient metabolic network with a novel twist.
by: Ryan J Mailloux, et al.
Published: (2007-08-01) -
Aluminum tolerance in Pseudomonas fluorescens ATCC 13525: involvement of a gelatinous lipid-rich residue/
by: 171307 Appanna, Vasu D., et al. -
The metabolic reprogramming evoked by nitrosative stress triggers the anaerobic utilization of citrate in Pseudomonas fluorescens.
by: Christopher Auger, et al.
Published: (2011-01-01) -
A novel strategy involved in [corrected] anti-oxidative defense: the conversion of NADH into NADPH by a metabolic network.
by: Ranji Singh, et al.
Published: (2008-01-01) -
Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1).
by: Joseph Lemire, et al.
Published: (2008-01-01)