Integral Role of PTP1B in Adiponectin-Mediated Inhibition of Oncogenic Actions of Leptin in Breast Carcinogenesis

Integral Role of PTP1B in Adiponectin-Mediated Inhibition of Oncogenic Actions of Leptin in Breast Carcinogenesis

The molecular effects of obesity are mediated by alterations in the levels of adipocytokines. High leptin level associated with obese state is a major cause of breast cancer progression and metastasis, whereas adiponectin is considered a “guardian angel adipocytokine” for its protective role against...

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Bibliographic Details
Main Authors: LaTonia Taliaferro-Smith, Arumugam Nagalingam, Brandi Brandon Knight, Elaine Oberlick, Neeraj K. Saxena, Dipali Sharma
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613801236

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