Independent component analysis recovers consistent regulatory signals from disparate datasets.
The availability of bacterial transcriptomes has dramatically increased in recent years. This data deluge could result in detailed inference of underlying regulatory networks, but the diversity of experimental platforms and protocols introduces critical biases that could hinder scalable analysis of...
Main Authors: | Anand V Sastry, Alyssa Hu, David Heckmann, Saugat Poudel, Erol Kavvas, Bernhard O Palsson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-02-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1008647 |
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