Taxonomic and functional profiling of fecal metagenomes for the early detection of colorectal cancer

Taxonomic and functional profiling of fecal metagenomes for the early detection of colorectal cancer

ObjectivesThis study aimed to identify colorectal cancer (CRC)-associated phylogenetic and functional bacterial features by a large-scale metagenomic sequencing and develop a binomial classifier to accurately distinguish between CRC patients and healthy individuals.MethodsWe conducted shotgun metage...

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Bibliographic Details
Main Authors: Xudong Wu, Zhimin Tang, Rongsong Zhao, Yusi Wang, Xianshu Wang, Side Liu, Hongzhi Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
metagenomic sequencing
fecal microbiota
bacterial biomarker
microbial taxonomy
functional pathways
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1218056/full

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