Rational design of a new Trypanosoma rangeli trans-sialidase for efficient sialylation of glycans.

Rational design of a new Trypanosoma rangeli trans-sialidase for efficient sialylation of glycans.

This paper reports rational engineering of Trypanosoma rangeli sialidase to develop an effective enzyme for a potentially important type of reactivity: production of sialylated prebiotic glycans. The Trypanosoma cruzi trans-sialidase and the homologous T. rangeli sialidase has previously been used t...

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Bibliographic Details
Main Authors:	Carsten Jers, Malwina Michalak, Dorte M Larsen, Kasper P Kepp, Haiying Li, Yao Guo, Finn Kirpekar, Anne S Meyer, Jørn D Mikkelsen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24404142/pdf/?tool=EBI

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