EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT
Abstract. We studied effects of Stimforte, an immunomodulatory drug of animal origin, upon mononuclear leukocytes (MLs) and morphology of lymphoid organs in the course of cyclophosphan-induced immunosuppression. It was demonstrated that Stimforte is able to correct the quantitative and s...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/500 |
| _version_ | 1797198027755094016 |
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| author | D. G. Maldov A. V. Ilychev E. A. Lebedinskaya E. V. Fadeeva O. V. Lebedinskaya N. K. Akhmatova V. A. Chetvertnykh A. P. Godovalov S. V. Melekhin M. V. Kiselevsky |
| author_facet | D. G. Maldov A. V. Ilychev E. A. Lebedinskaya E. V. Fadeeva O. V. Lebedinskaya N. K. Akhmatova V. A. Chetvertnykh A. P. Godovalov S. V. Melekhin M. V. Kiselevsky |
| author_sort | D. G. Maldov |
| collection | DOAJ |
| description | Abstract. We studied effects of Stimforte, an immunomodulatory drug of animal origin, upon mononuclear leukocytes (MLs) and morphology of lymphoid organs in the course of cyclophosphan-induced immunosuppression. It was demonstrated that Stimforte is able to correct the quantitative and subpopulational composition of splenic MLs, the structure of central and peripheral lymphopoietic tissues, as well as effector cell functions of innate immunity affected by the cytostatic drug. (Med. Immunol., 2011, vol. 13, N 2-3, pp 133-138) |
| first_indexed | 2024-03-08T05:50:45Z |
| format | Article |
| id | doaj.art-7ce5e89d1161473babc97583d78087c1 |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:53:20Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-7ce5e89d1161473babc97583d78087c12024-04-22T13:07:37ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-01132-313313810.15789/1563-0625-2011-2-3-133-138497EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENTD. G. Maldov0A. V. Ilychev1E. A. Lebedinskaya2E. V. Fadeeva3O. V. Lebedinskaya4N. K. AkhmatovaV. A. Chetvertnykh5A. P. Godovalov6S. V. Melekhin7M. V. Kiselevsky8ЗАО СКАЙ-ЛТД, МоскваЗАО СКАЙ-ЛТД, МоскваГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГУ «Российский онкологический научный центр им. Н.Н. Блохина РАМН», МоскваAbstract. We studied effects of Stimforte, an immunomodulatory drug of animal origin, upon mononuclear leukocytes (MLs) and morphology of lymphoid organs in the course of cyclophosphan-induced immunosuppression. It was demonstrated that Stimforte is able to correct the quantitative and subpopulational composition of splenic MLs, the structure of central and peripheral lymphopoietic tissues, as well as effector cell functions of innate immunity affected by the cytostatic drug. (Med. Immunol., 2011, vol. 13, N 2-3, pp 133-138)https://www.mimmun.ru/mimmun/article/view/500immune suppressioncyclophosphanstimforteimmunomodulatory drugs |
| spellingShingle | D. G. Maldov A. V. Ilychev E. A. Lebedinskaya E. V. Fadeeva O. V. Lebedinskaya N. K. Akhmatova V. A. Chetvertnykh A. P. Godovalov S. V. Melekhin M. V. Kiselevsky EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT Медицинская иммунология immune suppression cyclophosphan stimforte immunomodulatory drugs |
| title | EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT |
| title_full | EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT |
| title_fullStr | EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT |
| title_full_unstemmed | EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT |
| title_short | EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT |
| title_sort | effect of stimforte upon murine mononuclear leukocytes and lymphoid organs during cyclophosphan treatment |
| topic | immune suppression cyclophosphan stimforte immunomodulatory drugs |
| url | https://www.mimmun.ru/mimmun/article/view/500 |
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