An Alternative Approach for the Synthesis of Sulfoquinovosyldiacylglycerol
Sulfoquinovosyldiacylglycerol (SQDG) is a glycolipid ubiquitously found in photosynthetically active organisms. It has attracted much attention in recent years due to its biological activities. Similarly, the increasing demand for vegan and functional foods has led to a growing interest in micronutr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/14/4275 |
| _version_ | 1797526508742377472 |
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| author | Tobias Sitz Hendrik Domey Judith Fischer Sascha Rohn |
| author_facet | Tobias Sitz Hendrik Domey Judith Fischer Sascha Rohn |
| author_sort | Tobias Sitz |
| collection | DOAJ |
| description | Sulfoquinovosyldiacylglycerol (SQDG) is a glycolipid ubiquitously found in photosynthetically active organisms. It has attracted much attention in recent years due to its biological activities. Similarly, the increasing demand for vegan and functional foods has led to a growing interest in micronutrients such as sulfolipids and their physiological influence on human health. To study this influence, reference materials are needed for developing new analytical methods and providing enough material for model studies on the biological activity. However, the availability of these materials is limited by the difficulty to isolate and purify sulfolipids from natural sources and the unavailability of chemical standards on the market. Consequently, an alternative synthetic route for the comprehensive preparation of sulfolipids was established. Here, the synthesis of a sulfolipid with two identical saturated fatty acids is described exemplarily. The method opens possibilities for the preparation of a diverse range of interesting derivatives with different saturated and unsaturated fatty acids. |
| first_indexed | 2024-03-10T09:30:36Z |
| format | Article |
| id | doaj.art-7ceaa7bf32434d6eb4bd56e2a2dc225a |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T09:30:36Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-7ceaa7bf32434d6eb4bd56e2a2dc225a2023-11-22T04:31:17ZengMDPI AGMolecules1420-30492021-07-012614427510.3390/molecules26144275An Alternative Approach for the Synthesis of SulfoquinovosyldiacylglycerolTobias Sitz0Hendrik Domey1Judith Fischer2Sascha Rohn3Institute of Food Chemistry, Hamburg School of Food Science, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyInstitute of Food Chemistry, Hamburg School of Food Science, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyInstitute of Food Chemistry, Hamburg School of Food Science, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyInstitute of Food Chemistry, Hamburg School of Food Science, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanySulfoquinovosyldiacylglycerol (SQDG) is a glycolipid ubiquitously found in photosynthetically active organisms. It has attracted much attention in recent years due to its biological activities. Similarly, the increasing demand for vegan and functional foods has led to a growing interest in micronutrients such as sulfolipids and their physiological influence on human health. To study this influence, reference materials are needed for developing new analytical methods and providing enough material for model studies on the biological activity. However, the availability of these materials is limited by the difficulty to isolate and purify sulfolipids from natural sources and the unavailability of chemical standards on the market. Consequently, an alternative synthetic route for the comprehensive preparation of sulfolipids was established. Here, the synthesis of a sulfolipid with two identical saturated fatty acids is described exemplarily. The method opens possibilities for the preparation of a diverse range of interesting derivatives with different saturated and unsaturated fatty acids.https://www.mdpi.com/1420-3049/26/14/4275SQDGsulfoquinovosyldiacylglycerolsulfolipidssulfurtotal synthesis |
| spellingShingle | Tobias Sitz Hendrik Domey Judith Fischer Sascha Rohn An Alternative Approach for the Synthesis of Sulfoquinovosyldiacylglycerol Molecules SQDG sulfoquinovosyldiacylglycerol sulfolipids sulfur total synthesis |
| title | An Alternative Approach for the Synthesis of Sulfoquinovosyldiacylglycerol |
| title_full | An Alternative Approach for the Synthesis of Sulfoquinovosyldiacylglycerol |
| title_fullStr | An Alternative Approach for the Synthesis of Sulfoquinovosyldiacylglycerol |
| title_full_unstemmed | An Alternative Approach for the Synthesis of Sulfoquinovosyldiacylglycerol |
| title_short | An Alternative Approach for the Synthesis of Sulfoquinovosyldiacylglycerol |
| title_sort | alternative approach for the synthesis of sulfoquinovosyldiacylglycerol |
| topic | SQDG sulfoquinovosyldiacylglycerol sulfolipids sulfur total synthesis |
| url | https://www.mdpi.com/1420-3049/26/14/4275 |
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