Doxorubicin–Loaded Human Serum Albumin Submicron Particles: Preparation, Characterization and In Vitro Cellular Uptake

Doxorubicin–Loaded Human Serum Albumin Submicron Particles: Preparation, Characterization and In Vitro Cellular Uptake

Doxorubicin (DOX) is an effective anthracycline antibiotic drug which is commonly used in a broad range cancer therapy. However, due to dose depending side effects and toxicity to non-cancerous tissues, its clinical applications are restricted. To overcome these limitations, human serum albumin (HSA...

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Bibliographic Details
Main Authors: Saranya Chaiwaree, Ausanai Prapan, Nittiya Suwannasom, Tomás Laporte, Tanja Neumann, Axel Pruß, Radostina Georgieva, Hans Bäumler
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
doxorubicin
albumin particles
ccd technique
cellular uptake
submicron particles
Online Access:https://www.mdpi.com/1999-4923/12/3/224

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