Methods optimization for the expression and purification of human calcium calmodulin-dependent protein kinase II alpha.
Calcium/calmodulin-dependent protein kinase II (CaMKII) is a complex multifunctional kinase that is highly expressed in central nervous tissues and plays a key regulatory role in the calcium signaling pathway. Despite over 30 years of recombinant expression and characterization studies, CaMKII conti...
Main Authors: | Scott C Bolton, David H Thompson, Tamara L Kinzer-Ursem |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024-01-01
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Series: | PLoS ONE |
Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0285651&type=printable |
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