Cerebral Blood Flow in Healthy Subjects with Different Hypnotizability Scores
Hypnotizability is a cognitive trait associated with differences in the brachial artery flow-mediated dilatation of individuals with high hypnotizability (highs) and low hypnotizability scores (lows). The study investigated possible hypnotizability-related cerebrovascular differences. Among 24 healt...
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MDPI AG
2022-04-01
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| author | Anas Rashid Enrica Laura Santarcangelo Silvestro Roatta |
| author_facet | Anas Rashid Enrica Laura Santarcangelo Silvestro Roatta |
| author_sort | Anas Rashid |
| collection | DOAJ |
| description | Hypnotizability is a cognitive trait associated with differences in the brachial artery flow-mediated dilatation of individuals with high hypnotizability (highs) and low hypnotizability scores (lows). The study investigated possible hypnotizability-related cerebrovascular differences. Among 24 healthy volunteers, the Stanford Hypnotic Susceptibility Scale Form A identified 13 medium-to-lows (med-lows), 11 medium-to-highs (med-highs), and 1 medium hypnotizable. Hypnotizability did not influence the significant changes produced by the trail making task (TMT), mental arithmetic task (MAT), hyperventilation (HVT), and rebreathing (RBT) on heart rate (HR), arterial blood pressure (ABP), and partial pressure of end-tidal CO<sub>2</sub> (P<sub>ET</sub>CO<sub>2</sub>), but moderated the correlations between the changes occurring during tasks with respect to basal conditions (Δ) in ABP and P<sub>ET</sub>CO<sub>2</sub> with middle cerebral artery flow velocity (MCAv). In HVT, med-lows exhibited a significant correlation between ΔMCAv and ΔP<sub>ET</sub>CO<sub>2</sub>, and med-highs showed a significant correlation between ΔABP and ΔMCAv. Cerebrovascular reactivity (CVR) and conductance (ΔCVCi) were significantly correlated with ΔMCAv only in med-lows during HVT and RBT. For the first time, cerebrovascular reactivity related to hypnotizability was investigated, evidencing different correlations among hemodynamic variables in med-highs and med-lows. |
| first_indexed | 2024-03-10T03:14:38Z |
| format | Article |
| id | doaj.art-7cef7b95d2f341d4927eab87b40772c7 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T03:14:38Z |
| publishDate | 2022-04-01 |
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| series | Brain Sciences |
| spelling | doaj.art-7cef7b95d2f341d4927eab87b40772c72023-11-23T10:17:05ZengMDPI AGBrain Sciences2076-34252022-04-0112555810.3390/brainsci12050558Cerebral Blood Flow in Healthy Subjects with Different Hypnotizability ScoresAnas Rashid0Enrica Laura Santarcangelo1Silvestro Roatta2Lab of Integrative Physiology, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, 10125 Torino, ItalyLab of Cognitive and Behavioral Neuroscience, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56127 Pisa, ItalyLab of Integrative Physiology, Department of Neuroscience “Rita Levi Montalcini”, University of Torino, 10125 Torino, ItalyHypnotizability is a cognitive trait associated with differences in the brachial artery flow-mediated dilatation of individuals with high hypnotizability (highs) and low hypnotizability scores (lows). The study investigated possible hypnotizability-related cerebrovascular differences. Among 24 healthy volunteers, the Stanford Hypnotic Susceptibility Scale Form A identified 13 medium-to-lows (med-lows), 11 medium-to-highs (med-highs), and 1 medium hypnotizable. Hypnotizability did not influence the significant changes produced by the trail making task (TMT), mental arithmetic task (MAT), hyperventilation (HVT), and rebreathing (RBT) on heart rate (HR), arterial blood pressure (ABP), and partial pressure of end-tidal CO<sub>2</sub> (P<sub>ET</sub>CO<sub>2</sub>), but moderated the correlations between the changes occurring during tasks with respect to basal conditions (Δ) in ABP and P<sub>ET</sub>CO<sub>2</sub> with middle cerebral artery flow velocity (MCAv). In HVT, med-lows exhibited a significant correlation between ΔMCAv and ΔP<sub>ET</sub>CO<sub>2</sub>, and med-highs showed a significant correlation between ΔABP and ΔMCAv. Cerebrovascular reactivity (CVR) and conductance (ΔCVCi) were significantly correlated with ΔMCAv only in med-lows during HVT and RBT. For the first time, cerebrovascular reactivity related to hypnotizability was investigated, evidencing different correlations among hemodynamic variables in med-highs and med-lows.https://www.mdpi.com/2076-3425/12/5/558TCDNIRShyperventilationrebreathingcognitive taskshypnotic susceptibility |
| spellingShingle | Anas Rashid Enrica Laura Santarcangelo Silvestro Roatta Cerebral Blood Flow in Healthy Subjects with Different Hypnotizability Scores Brain Sciences TCD NIRS hyperventilation rebreathing cognitive tasks hypnotic susceptibility |
| title | Cerebral Blood Flow in Healthy Subjects with Different Hypnotizability Scores |
| title_full | Cerebral Blood Flow in Healthy Subjects with Different Hypnotizability Scores |
| title_fullStr | Cerebral Blood Flow in Healthy Subjects with Different Hypnotizability Scores |
| title_full_unstemmed | Cerebral Blood Flow in Healthy Subjects with Different Hypnotizability Scores |
| title_short | Cerebral Blood Flow in Healthy Subjects with Different Hypnotizability Scores |
| title_sort | cerebral blood flow in healthy subjects with different hypnotizability scores |
| topic | TCD NIRS hyperventilation rebreathing cognitive tasks hypnotic susceptibility |
| url | https://www.mdpi.com/2076-3425/12/5/558 |
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