High-Throughput IgG Epitope Mapping of Tetanus Neurotoxin: Implications for Immunotherapy and Vaccine Design
Tetanus is an acute, fatal disease caused by exotoxins released from <i>Clostridium tetani</i> during infections. A protective humoral immune response can be induced by vaccinations with pediatric and booster combinatorial vaccines that contain inactivated tetanus neurotoxin (TeNT) as a...
Main Authors: | Salvatore G. De-Simone, Paloma Napoleão-Pêgo, Guilherme C. Lechuga, João P. R. S. Carvalho, Larissa R. Gomes, Sergian V. Cardozo, Carlos M. Morel, David W. Provance, Flavio R. da Silva |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/15/4/239 |
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