Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired Cats
The detection of subtle changes in the pituitary dimensions has relevant clinical implications. In cats, a few studies have established the cut-off values of the pituitary gland’s dimensions using small and inhomogeneous samples. The aims of this study were: to determine by computed tomography (CT)...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
|
| Series: | Animals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2615/13/12/1935 |
| _version_ | 1827738913605681152 |
|---|---|
| author | Dario Costanza Pierpaolo Coluccia Luigi Auletta Erica Castiello Luigi Navas Adelaide Greco Leonardo Meomartino |
| author_facet | Dario Costanza Pierpaolo Coluccia Luigi Auletta Erica Castiello Luigi Navas Adelaide Greco Leonardo Meomartino |
| author_sort | Dario Costanza |
| collection | DOAJ |
| description | The detection of subtle changes in the pituitary dimensions has relevant clinical implications. In cats, a few studies have established the cut-off values of the pituitary gland’s dimensions using small and inhomogeneous samples. The aims of this study were: to determine by computed tomography (CT) the pituitary linear dimensions and the pituitary-to-brain (P:B) ratio in a sample of domestic short-haired (DSH) cats; to assess the effects of sex, age, and weight on pituitary dimensions; and to evaluate the inter- and intra-observer agreement for such measurements. All skull CTs of DSH cats performed over four years using a multidetector CT and a standardized protocol were retrospectively reviewed. The exclusion criteria were: clinical, laboratory, or CT alterations of the pituitary gland, brain diseases, fractures of the neurocranium, and diabetes. The pituitary dimensions and brain area were assessed by two different observers using multiplanar reconstructions and automated segmentation tools. Fifty-one cats were included in the final sample. The intraclass correlation coefficients for intra- and inter-observer reliability were good/excellent, and moderate/good, respectively. No differences between sexes were detected, and negligible correlations were found between age and weight. According to this study, a pituitary gland with a height > 4 mm or a P:B ratio > 0.49 mm should be considered enlarged. |
| first_indexed | 2024-03-11T02:50:44Z |
| format | Article |
| id | doaj.art-7cf2650fa05f47688d18bc46ca60f8a9 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T02:50:44Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-7cf2650fa05f47688d18bc46ca60f8a92023-11-18T08:58:17ZengMDPI AGAnimals2076-26152023-06-011312193510.3390/ani13121935Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired CatsDario Costanza0Pierpaolo Coluccia1Luigi Auletta2Erica Castiello3Luigi Navas4Adelaide Greco5Leonardo Meomartino6Interdepartmental Center of Veterinary Radiology, University of Napoli “Federico II”, Via Federico Delpino 1, 80137 Napoli, ItalyInterdepartmental Center of Veterinary Radiology, University of Napoli “Federico II”, Via Federico Delpino 1, 80137 Napoli, ItalyDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milano, Via dell’Università 6, 26900 Lodi, ItalyInterdepartmental Center of Veterinary Radiology, University of Napoli “Federico II”, Via Federico Delpino 1, 80137 Napoli, ItalyDepartment of Veterinary Medicine and Animal Production, University of Napoli “Federico II”, Via Federico Delpino 1, 80137 Napoli, ItalyInterdepartmental Center of Veterinary Radiology, University of Napoli “Federico II”, Via Federico Delpino 1, 80137 Napoli, ItalyInterdepartmental Center of Veterinary Radiology, University of Napoli “Federico II”, Via Federico Delpino 1, 80137 Napoli, ItalyThe detection of subtle changes in the pituitary dimensions has relevant clinical implications. In cats, a few studies have established the cut-off values of the pituitary gland’s dimensions using small and inhomogeneous samples. The aims of this study were: to determine by computed tomography (CT) the pituitary linear dimensions and the pituitary-to-brain (P:B) ratio in a sample of domestic short-haired (DSH) cats; to assess the effects of sex, age, and weight on pituitary dimensions; and to evaluate the inter- and intra-observer agreement for such measurements. All skull CTs of DSH cats performed over four years using a multidetector CT and a standardized protocol were retrospectively reviewed. The exclusion criteria were: clinical, laboratory, or CT alterations of the pituitary gland, brain diseases, fractures of the neurocranium, and diabetes. The pituitary dimensions and brain area were assessed by two different observers using multiplanar reconstructions and automated segmentation tools. Fifty-one cats were included in the final sample. The intraclass correlation coefficients for intra- and inter-observer reliability were good/excellent, and moderate/good, respectively. No differences between sexes were detected, and negligible correlations were found between age and weight. According to this study, a pituitary gland with a height > 4 mm or a P:B ratio > 0.49 mm should be considered enlarged.https://www.mdpi.com/2076-2615/13/12/1935acromegalyadenomadiabetesfelinehypophysismicroadenoma |
| spellingShingle | Dario Costanza Pierpaolo Coluccia Luigi Auletta Erica Castiello Luigi Navas Adelaide Greco Leonardo Meomartino Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired Cats Animals acromegaly adenoma diabetes feline hypophysis microadenoma |
| title | Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired Cats |
| title_full | Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired Cats |
| title_fullStr | Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired Cats |
| title_full_unstemmed | Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired Cats |
| title_short | Computed Tomographic Assessment of Pituitary Gland Dimensions in Domestic Short-Haired Cats |
| title_sort | computed tomographic assessment of pituitary gland dimensions in domestic short haired cats |
| topic | acromegaly adenoma diabetes feline hypophysis microadenoma |
| url | https://www.mdpi.com/2076-2615/13/12/1935 |
| work_keys_str_mv | AT dariocostanza computedtomographicassessmentofpituitaryglanddimensionsindomesticshorthairedcats AT pierpaolocoluccia computedtomographicassessmentofpituitaryglanddimensionsindomesticshorthairedcats AT luigiauletta computedtomographicassessmentofpituitaryglanddimensionsindomesticshorthairedcats AT ericacastiello computedtomographicassessmentofpituitaryglanddimensionsindomesticshorthairedcats AT luiginavas computedtomographicassessmentofpituitaryglanddimensionsindomesticshorthairedcats AT adelaidegreco computedtomographicassessmentofpituitaryglanddimensionsindomesticshorthairedcats AT leonardomeomartino computedtomographicassessmentofpituitaryglanddimensionsindomesticshorthairedcats |