A CASE OF FASCIOLOSIS PRESENTING WITH SEVERE HYPEREOSINOPHILIA
Objective: Fasciola hepatica is a parasitic ttrematode and infects livers of various mammals and rarely infects human liver. Frequently eosinophilia is detected in laboratory findings, but it is generally mild or moderate as with other parasitic infections. Here we present a patient with Fasciolosis...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-10-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137922013785 |
| _version_ | 1817969270797107200 |
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| author | Metban Mastanzade Arzu Şenol Alper Koç |
| author_facet | Metban Mastanzade Arzu Şenol Alper Koç |
| author_sort | Metban Mastanzade |
| collection | DOAJ |
| description | Objective: Fasciola hepatica is a parasitic ttrematode and infects livers of various mammals and rarely infects human liver. Frequently eosinophilia is detected in laboratory findings, but it is generally mild or moderate as with other parasitic infections. Here we present a patient with Fasciolosis as the cause of severe hypereosiphilia. Case report: A 66-year-old female patient presented with weight loss, nausea and abdominal pain for one month. Her physical examination was unremarkable except for mild hepatomegaly. Her laboratory tests were as follows; leukocytes 29900/mm3, eosinophils 21550/mm3 (%71.9), ALP 379 IU/L, LDH 278 IU/L, GGT 53 IU/L, CRP 30 mg/dl. All other etiological tests including primary secondary causes were negative.Abdominal MRI revealed focal patchy nodular lesions. Fasciola hepatica IHA (1/2560) was positive. Results: After the diagnosis, the patient was administered 2 doses of triclabendazole (10 mg/mg) at 5 day intervals. In the 3rd month of the treatment, the control eosinophil count decreased to 480/ mm3, and the patient was free of any symptoms. Conclusion: Severe eosinophilia (>5000/mm3) is generally associated with malignant diseases, hypereosinophilic syndrome or primary hematologic disorders. But it would be useful to consider fasciolosis in hypereosinophilia patients who are sheep and cattle breeder and present with gastrointestinal system complaints such as jaundice and abdominal pain. |
| first_indexed | 2024-04-13T20:19:09Z |
| format | Article |
| id | doaj.art-7cf30456b973495799dbaa2ab1fb1e94 |
| institution | Directory Open Access Journal |
| issn | 2531-1379 |
| language | English |
| last_indexed | 2024-04-13T20:19:09Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Hematology, Transfusion and Cell Therapy |
| spelling | doaj.art-7cf30456b973495799dbaa2ab1fb1e942022-12-22T02:31:36ZengElsevierHematology, Transfusion and Cell Therapy2531-13792022-10-0144S35A CASE OF FASCIOLOSIS PRESENTING WITH SEVERE HYPEREOSINOPHILIAMetban Mastanzade0Arzu Şenol1Alper Koç2Elazığ Fethi Sekin City HospitalElazığ Fethi Sekin City HospitalElazığ Fethi Sekin City HospitalObjective: Fasciola hepatica is a parasitic ttrematode and infects livers of various mammals and rarely infects human liver. Frequently eosinophilia is detected in laboratory findings, but it is generally mild or moderate as with other parasitic infections. Here we present a patient with Fasciolosis as the cause of severe hypereosiphilia. Case report: A 66-year-old female patient presented with weight loss, nausea and abdominal pain for one month. Her physical examination was unremarkable except for mild hepatomegaly. Her laboratory tests were as follows; leukocytes 29900/mm3, eosinophils 21550/mm3 (%71.9), ALP 379 IU/L, LDH 278 IU/L, GGT 53 IU/L, CRP 30 mg/dl. All other etiological tests including primary secondary causes were negative.Abdominal MRI revealed focal patchy nodular lesions. Fasciola hepatica IHA (1/2560) was positive. Results: After the diagnosis, the patient was administered 2 doses of triclabendazole (10 mg/mg) at 5 day intervals. In the 3rd month of the treatment, the control eosinophil count decreased to 480/ mm3, and the patient was free of any symptoms. Conclusion: Severe eosinophilia (>5000/mm3) is generally associated with malignant diseases, hypereosinophilic syndrome or primary hematologic disorders. But it would be useful to consider fasciolosis in hypereosinophilia patients who are sheep and cattle breeder and present with gastrointestinal system complaints such as jaundice and abdominal pain.http://www.sciencedirect.com/science/article/pii/S2531137922013785 |
| spellingShingle | Metban Mastanzade Arzu Şenol Alper Koç A CASE OF FASCIOLOSIS PRESENTING WITH SEVERE HYPEREOSINOPHILIA Hematology, Transfusion and Cell Therapy |
| title | A CASE OF FASCIOLOSIS PRESENTING WITH SEVERE HYPEREOSINOPHILIA |
| title_full | A CASE OF FASCIOLOSIS PRESENTING WITH SEVERE HYPEREOSINOPHILIA |
| title_fullStr | A CASE OF FASCIOLOSIS PRESENTING WITH SEVERE HYPEREOSINOPHILIA |
| title_full_unstemmed | A CASE OF FASCIOLOSIS PRESENTING WITH SEVERE HYPEREOSINOPHILIA |
| title_short | A CASE OF FASCIOLOSIS PRESENTING WITH SEVERE HYPEREOSINOPHILIA |
| title_sort | case of fasciolosis presenting with severe hypereosinophilia |
| url | http://www.sciencedirect.com/science/article/pii/S2531137922013785 |
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