Photoplethysmography for demarcation of cutaneous squamous cell carcinoma
Abstract A video processing algorithm designed to identify cancer suspicious skin areas is presented here. It is based on video recordings of squamous cell carcinoma in the skin. Squamous cell carcinoma is a common malignancy, normally treated by surgical removal. The surgeon should always balance s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-11-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-00645-4 |
| _version_ | 1819008711709949952 |
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| author | Simon Mylius Rasmussen Thomas Nielsen Sofie Hody Henrik Hager Lars Peter Schousboe |
| author_facet | Simon Mylius Rasmussen Thomas Nielsen Sofie Hody Henrik Hager Lars Peter Schousboe |
| author_sort | Simon Mylius Rasmussen |
| collection | DOAJ |
| description | Abstract A video processing algorithm designed to identify cancer suspicious skin areas is presented here. It is based on video recordings of squamous cell carcinoma in the skin. Squamous cell carcinoma is a common malignancy, normally treated by surgical removal. The surgeon should always balance sufficient tissue removal against unnecessary mutilation, and therefore methods for distinction of cancer boundaries are wanted. Squamous cell carcinoma has angiogenesis and increased blood supply. Remote photoplethysmography is an evolving technique for analysis of signal variations in video recordings in order to extract vital signs such as pulsation. We hypothesize that the remote photoplethysmography signal inside the area of a squamous cell carcinoma is significantly different from the surrounding healthy skin. Based on high speed video recordings of 13 patients with squamous cell carcinoma, we have examined temporal signal differences in cancer areas versus healthy skin areas. A significant difference in temporal signal changes between cancer areas and healthy areas was found. Our video processing algorithm showed promising results encouraging further investigation to clarify how detailed distinctions can be made. |
| first_indexed | 2024-12-21T00:44:49Z |
| format | Article |
| id | doaj.art-7cf8902454e34f9784248471d7b44f6a |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-21T00:44:49Z |
| publishDate | 2021-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-7cf8902454e34f9784248471d7b44f6a2022-12-21T19:21:33ZengNature PortfolioScientific Reports2045-23222021-11-011111710.1038/s41598-021-00645-4Photoplethysmography for demarcation of cutaneous squamous cell carcinomaSimon Mylius Rasmussen0Thomas Nielsen1Sofie Hody2Henrik Hager3Lars Peter Schousboe4Department of Otolaryngology at the Southdanish University HospitalDepartment of Electrical and Computer Engineering, Aarhus UniversityDepartment of Plastic SurgeryDepartment of Clinical Pathology, Vejle HospitalDepartment of Otolaryngology at the Southdanish University HospitalAbstract A video processing algorithm designed to identify cancer suspicious skin areas is presented here. It is based on video recordings of squamous cell carcinoma in the skin. Squamous cell carcinoma is a common malignancy, normally treated by surgical removal. The surgeon should always balance sufficient tissue removal against unnecessary mutilation, and therefore methods for distinction of cancer boundaries are wanted. Squamous cell carcinoma has angiogenesis and increased blood supply. Remote photoplethysmography is an evolving technique for analysis of signal variations in video recordings in order to extract vital signs such as pulsation. We hypothesize that the remote photoplethysmography signal inside the area of a squamous cell carcinoma is significantly different from the surrounding healthy skin. Based on high speed video recordings of 13 patients with squamous cell carcinoma, we have examined temporal signal differences in cancer areas versus healthy skin areas. A significant difference in temporal signal changes between cancer areas and healthy areas was found. Our video processing algorithm showed promising results encouraging further investigation to clarify how detailed distinctions can be made.https://doi.org/10.1038/s41598-021-00645-4 |
| spellingShingle | Simon Mylius Rasmussen Thomas Nielsen Sofie Hody Henrik Hager Lars Peter Schousboe Photoplethysmography for demarcation of cutaneous squamous cell carcinoma Scientific Reports |
| title | Photoplethysmography for demarcation of cutaneous squamous cell carcinoma |
| title_full | Photoplethysmography for demarcation of cutaneous squamous cell carcinoma |
| title_fullStr | Photoplethysmography for demarcation of cutaneous squamous cell carcinoma |
| title_full_unstemmed | Photoplethysmography for demarcation of cutaneous squamous cell carcinoma |
| title_short | Photoplethysmography for demarcation of cutaneous squamous cell carcinoma |
| title_sort | photoplethysmography for demarcation of cutaneous squamous cell carcinoma |
| url | https://doi.org/10.1038/s41598-021-00645-4 |
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