Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia
Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with de...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21022-9 |
| _version_ | 1818424766309072896 |
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| author | Carmen Gasca-Salas Beatriz Fernández-Rodríguez José A. Pineda-Pardo Rafael Rodríguez-Rojas Ignacio Obeso Frida Hernández-Fernández Marta del Álamo David Mata Pasqualina Guida Carlos Ordás-Bandera J. Ignacio Montero-Roblas Raúl Martínez-Fernández Guglielmo Foffani Itay Rachmilevitch José A. Obeso |
| author_facet | Carmen Gasca-Salas Beatriz Fernández-Rodríguez José A. Pineda-Pardo Rafael Rodríguez-Rojas Ignacio Obeso Frida Hernández-Fernández Marta del Álamo David Mata Pasqualina Guida Carlos Ordás-Bandera J. Ignacio Montero-Roblas Raúl Martínez-Fernández Guglielmo Foffani Itay Rachmilevitch José A. Obeso |
| author_sort | Carmen Gasca-Salas |
| collection | DOAJ |
| description | Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with dementia. |
| first_indexed | 2024-12-14T14:03:15Z |
| format | Article |
| id | doaj.art-7cf8f633f4864b079a9626f71c959e9a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T14:03:15Z |
| publishDate | 2021-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-7cf8f633f4864b079a9626f71c959e9a2022-12-21T22:58:40ZengNature PortfolioNature Communications2041-17232021-02-011211710.1038/s41467-021-21022-9Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementiaCarmen Gasca-Salas0Beatriz Fernández-Rodríguez1José A. Pineda-Pardo2Rafael Rodríguez-Rojas3Ignacio Obeso4Frida Hernández-Fernández5Marta del Álamo6David Mata7Pasqualina Guida8Carlos Ordás-Bandera9J. Ignacio Montero-Roblas10Raúl Martínez-Fernández11Guglielmo Foffani12Itay Rachmilevitch13José A. Obeso14HM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHospital Universitario Rey Juan CarlosIntensive care Unit, University Hospital HM Puerta del SurHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityInsightec LTDHM CINAC, Fundación HM Hospitales de Madrid, University Hospital HM Puerta del Sur. CEU-San Pablo UniversityBlood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with dementia.https://doi.org/10.1038/s41467-021-21022-9 |
| spellingShingle | Carmen Gasca-Salas Beatriz Fernández-Rodríguez José A. Pineda-Pardo Rafael Rodríguez-Rojas Ignacio Obeso Frida Hernández-Fernández Marta del Álamo David Mata Pasqualina Guida Carlos Ordás-Bandera J. Ignacio Montero-Roblas Raúl Martínez-Fernández Guglielmo Foffani Itay Rachmilevitch José A. Obeso Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia Nature Communications |
| title | Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia |
| title_full | Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia |
| title_fullStr | Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia |
| title_full_unstemmed | Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia |
| title_short | Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia |
| title_sort | blood brain barrier opening with focused ultrasound in parkinson s disease dementia |
| url | https://doi.org/10.1038/s41467-021-21022-9 |
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