Systems analysis of barrier molecule and ARNT-related gene expression regulation in melanoma

Systems analysis of barrier molecule and ARNT-related gene expression regulation in melanoma

Background: We have identified, in melanomas, a set of genes encoding proteins that mediate mechanical barrier function in normal skin (barrier molecule genes, BMGs) and whose overexpression is associated with decreased immune signatures and shorter patient survival. The most overexpressed of these,...

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Bibliographic Details
Main Authors:	Katie M. Leick, Joseph M. Obeid, Stefan Bekiranov, Craig L. Slingluff
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2019-12-01
Series:	OncoImmunology
Subjects:	barrier molecule genes epidermal differentiation complex melanoma aryl hydrocarbon receptor aryl hydrocarbon receptor nuclear translocator chromosome 1q21.3 copy number gain
Online Access:	http://dx.doi.org/10.1080/2162402X.2019.1665978

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