Selection of Effective Therapies Using Three-Dimensional in vitro Modeling of Chondrosarcoma

Selection of Effective Therapies Using Three-Dimensional in vitro Modeling of Chondrosarcoma

Purpose: Chondrosarcomas are a group of cartilaginous malignant neoplasms characterized by the deposition of chondrogenic extracellular matrix. Surgical resection is currently the only curative treatment option, due to their high resistance to conventional chemotherapy and radiotherapy. Novel therap...

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Bibliographic Details
Main Authors: Ieva Palubeckaitė, Sanne Venneker, Inge H. Briaire-de Bruijn, Brendy E. van den Akker, Augustinus D. Krol, Hans Gelderblom, Judith V. M. G. Bovée
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
chondrosarcoma
3D cell culture
chemotherapy
radiotherapy
clonal spheroids
sarcoma
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.566291/full

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