Sex at the interface: the origin and impact of sex differences in the developing human placenta

Sex at the interface: the origin and impact of sex differences in the developing human placenta

Highlights Placental sex differences exist from early prenatal development, and may help explain sex differences in pregnancy outcomes. Transcriptome profiling of early to mid-gestation placenta reveals that immune signaling is a hub of early prenatal sex differences. Differentially expressed genes...

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Bibliographic Details
Main Authors: Amy E. Braun, Olivia R. Mitchel, Tania L. Gonzalez, Tianyanxin Sun, Amy E. Flowers, Margareta D. Pisarska, Virginia D. Winn
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Biology of Sex Differences
Subjects:
Sex
Placenta
Differences
Gene expression
Fetal
Transcriptome
Online Access:https://doi.org/10.1186/s13293-022-00459-7

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