Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane

Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane

ABSTRACT Toxoplasma gondii is a ubiquitous, intracellular parasite that envelops its parasitophorous vacuole with a protein-laden membrane (PVM). The PVM is critical for interactions with the infected host cell, such as nutrient transport and immune defense. Only a few parasite and host proteins hav...

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Bibliographic Details
Main Authors: Alicja M. Cygan, Pierre M. Jean Beltran, Alma G. Mendoza, Tess C. Branon, Alice Y. Ting, Steven A. Carr, John C. Boothroyd
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:mBio
Subjects:
Toxoplasma
proximity-labeling
quantitative proteomics
Online Access:https://journals.asm.org/doi/10.1128/mBio.00260-21

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