Unintended Side Effects of Transformation Are Very Rare in Cryptococcus neoformans

Unintended Side Effects of Transformation Are Very Rare in Cryptococcus neoformans

Received wisdom in the field of fungal biology holds that the process of editing a genome by transformation and homologous recombination is inherently mutagenic. However, that belief is based on circumstantial evidence. We provide the first direct measurement of the effects of transformation on a fu...

Full description

Bibliographic Details
Main Authors:	Ryan Z. Friedman, Stacey R. Gish, Holly Brown, Lindsey Brier, Nicole Howard, Tamara L. Doering, Michael R. Brent
Format:	Article
Language:	English
Published:	Oxford University Press 2018-03-01
Series:	G3: Genes, Genomes, Genetics
Subjects:	Reverse genetics gene deletion yeasts genome sequence Cryptococcus neoformans strain KN99
Online Access:	http://g3journal.org/lookup/doi/10.1534/g3.117.300357

Similar Items

Immune evasion by Cryptococcus gattii in vaccinated mice coinfected with C. neoformans
by: Maureen M. Hester, et al.
Published: (2024-02-01)

The Buoyancy of <italic toggle="yes">Cryptococcus neoformans</italic> Is Affected by Capsule Size
by: Raghav Vij, et al.
Published: (2018-12-01)

Cutaneous lesions in the setting of disseminated Cryptococcus neoformans infection
by: Mithra John, et al.
Published: (2021-10-01)

Cryptococcus neoformans isolados de pacientes com AIDS
by: Fernandes Orionalda de F.L., et al.
Published: (2000-01-01)

Superoxide dismutase in Cryptococcus neoformans varieties gattii, grubi, and neoformans
by: ALT Dias, et al.
Published: (2006-02-01)

Antifungal Activity of Soil Streptomyces Isolates Against Cryptococcus neoformans
by: Başaran Dülger, et al.
Published: (2021-04-01)

Peeling the onion: the outer layers of Cryptococcus neoformans
by: Daniel P Agustinho, et al.
Published: (2018-05-01)

Tipificación molecular de aislamientos del complejo Cryptococcus neoformans/Cryptococcus gattii Molecular typing of the Cryptococcus neoformans/Cryptococcus gattii species complex
by: Patricia Escandón, et al.
Published: (2010-12-01)

A novel approach for locating mice brain regions of Cryptococcus neoformans CNS invasion
by: Chunting He, et al.
Published: (2016-04-01)

Regional pattern of the molecular types of Cryptococcus neoformans and Cryptococcus gattii in Brazil
by: Luciana Trilles, et al.
Published: (2008-08-01)

immunopathological study of the fungus cryptococcus neoformans in mice
by: F. A . Mahmood
Published: (2019-08-01)

Biological activity of Cryptococcus neoformans and Cryptococcus gattii from clinical and environmental isolates
by: Antonio Marcio Barbosa Junior, et al.
Published: (2013-06-01)

Persisting Cryptococcus yeast species Vishniacozyma victoriae and Cryptococcus neoformans elicit unique airway inflammation in mice following repeated exposure
by: Rachael E. Rush, et al.
Published: (2023-02-01)

A novel approach for locating mice brain regions of <i>Cryptococcus neoformans</i> CNS invasion
by: Chunting He, et al.
Published: (2016-03-01)

Corrigendum: Persisting Cryptococcus yeast species Vishniacozyma victoriae and Cryptococcus neoformans elicit unique airway inflammation in mice following repeated exposure
by: Rachael E. Rush, et al.
Published: (2024-02-01)

Disseminated Cryptococcus neoformans infection associated to COVID-19
by: Diana Alegre-González, et al.
Published: (2021-12-01)

Hipogamaglobulinemia como fator de risco para infecção por Cryptococcus neoformans: a propósito de dois casos Hypogammaglobulinemia as predisposing factor for Cryptococcus neoformans infection: regarding two cases
by: Roberto da Justa Pires Neto, et al.
Published: (2000-12-01)

Can smoking cause melanization of Cryptococcus neoformans in vivo?
by: Sabesan, G., et al.
Published: (2011-01-01)

Cryptococcus neoformans causing meningitis in AIDS patients
by: Everardo Albuquerque Menezes, et al.
Published: (2002-10-01)

Suscetibilidade a antifúngicos de variedades de Cryptococcus neoformans isoladas de pacientes em hospital universitário Susceptibility to antifungal agents among Cryptococcus neoformans varieties isolated from patients at a university hospital
by: Paulo Roberto da Silva, et al.
Published: (2008-04-01)

A Quick reCAP: Discovering <i>Cryptococcus neoformans</i> Capsule Mutants
by: Daphne Boodwa-Ko, et al.
Published: (2024-01-01)

Maintenance of Mitochondrial Morphology in <named-content content-type="genus-species">Cryptococcus neoformans</named-content> Is Critical for Stress Resistance and Virulence
by: Andrew L. Chang, et al.
Published: (2018-12-01)

Antifungal Susceptibilities of Cryptococcus neoformans
by: Lennox K. Archibald, et al.
Published: (2004-01-01)

Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans
by: Ye-Eun Son, et al.
Published: (2018-04-01)

Prevalência de Cryptococcus neoformans nos pombos urbanos da cidade de Porto Alegre, Rio Grande do Sul Prevalence of Cryptococcus neoformans in urban pigeons of Porto Alegre (RS), Brazil
by: Aline Reolon, et al.
Published: (2004-10-01)

Central venous catheter-related bloodstream infection and Cryptococcus neoformans
by: Felipe F. Tuon, et al.

Infratentorial Cryptococcus neoformans meningoencephalitis with cerebellar infarction: A rare case report
by: Zhaobo Shi, et al.
Published: (2022-12-01)

Cryptococcus neoformans and Cryptococcus gattii clinical isolates from Thailand display diverse phenotypic interactions with macrophages
by: Adithap Hansakon, et al.
Published: (2019-01-01)

Antifungal and Anti-Biofilm Activity of Essential Oil Active Components against Cryptococcus neoformans and Cryptococcus laurentii
by: Poonam Kumari, et al.
Published: (2017-11-01)

First isolation of Cryptococcus gattii molecular type VGII and Cryptococcus neoformans molecular type VNI from environmental sources in the city of Belém, Pará, Brazil
by: Solange do PSE Costa, et al.
Published: (2009-07-01)

Ergosterol Is Critical for Sporogenesis in <i>Cryptococcus neoformans</i>
by: Amber R. Matha, et al.
Published: (2024-01-01)

Synergistic effect of ibuprofen with itraconazole and fluconazole against Cryptococcus neoformans
by: Letícia Fernandes da Rocha, et al.
Published: (2020-09-01)

Cryptococcus Neoformans en excretas de palomas, suelo y aire de los palomares del perímetro Urbano de Ica, 2002
by: Maria Curo, et al.
Published: (2005-10-01)

Systematic review on Cryptococcus neoformans/Cryptococcus gattii species complex infections with recommendations for practice in health and care settings
by: Mireille H. van der Torre, et al.
Published: (2022-07-01)

EVALUATION OF THE ANTIFUNGAL SUSCEPTIBILITY AND KARYOTYPE OF Cryptococcus neoformans ISOLATED FROM CLINICAL SAMPLES IN VENEZUELA
by: B Calvo, et al.
Published: (2000-03-01)

Cryptococcus neoformans meningitis in a Non-HIV infected, nonorgan transplant, immunocompromised individual
by: Sandhya Manorenj, et al.
Published: (2018-01-01)

Rapid duplex flap probe-based isothermal assay to identify the Cryptococcus neoformans and Cryptococcus gattii
by: Xin Ye, et al.
Published: (2024-03-01)

Crecimiento del complejo Cryptococcus neoformans/ Cryptococcus gattiien extractos de excretas de palomas
by: Luz Dary Caicedo Bejarano, et al.
Published: (2020-01-01)

Genotypes of Cryptococcus neoformans and Cryptococcus gattii as agents of endemic cryptococcosis in Teresina, Piauí (northeastern Brazil)
by: Liline Maria Soares Martins, et al.
Published: (2011-09-01)

Ocorrência de Cryptococcus neoformans em excretas de pombos na cidade de Pelotas, Estado do Rio Grande do Sul Occurrence of Cryptococcus neoformans in pigeon excrement in the city of Pelotas, State of Rio Grande do Sul
by: Renata Osório de Faria, et al.
Published: (2010-04-01)