Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya.
Cryptosporidium is a leading cause of pediatric diarrhea in resource-limited settings; yet, few studies report the health care costs or societal impacts of this protozoan parasite. Our study examined direct and indirect costs associated with symptomatic cryptosporidiosis in infants younger than 12 m...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5568228?pdf=render |
| _version_ | 1819020878350909440 |
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| author | Ellen R Rafferty Janna M Schurer Michael B Arndt Robert K M Choy Eugenio L de Hostos David Shoultz Marwa Farag |
| author_facet | Ellen R Rafferty Janna M Schurer Michael B Arndt Robert K M Choy Eugenio L de Hostos David Shoultz Marwa Farag |
| author_sort | Ellen R Rafferty |
| collection | DOAJ |
| description | Cryptosporidium is a leading cause of pediatric diarrhea in resource-limited settings; yet, few studies report the health care costs or societal impacts of this protozoan parasite. Our study examined direct and indirect costs associated with symptomatic cryptosporidiosis in infants younger than 12 months in Kenya, Peru and Bangladesh. Inputs to the economic burden model, such as disease incidence, population size, health care seeking behaviour, hospital costs, travel costs, were extracted from peer-reviewed literature, government documents, and internationally validated statistical tools for each country. Indirect losses (i.e. caregiver income loss, mortality, and growth faltering) were also estimated. Our findings suggest that direct treatment costs per symptomatic cryptosporidiosis episode were highest in Kenya ($59.01), followed by Peru ($23.32), and Bangladesh ($7.62). The total annual economic impacts for the 0-11 month cohorts were highest in Peru ($41.5M; range $0.88-$599.3M), followed by Kenya ($37.4M; range $1.6-$804.5M) and Bangladesh ($9.6M, range $0.28-$91.5M). For all scenarios, indirect societal costs far outweighed direct treatment costs. These results highlight the critical need for innovative improvements to current prevention, diagnostic and treatment strategies available in resource poor settings, as well as the need for solutions that span multiple disciplines including food and water safety, sanitation and livestock production. |
| first_indexed | 2024-12-21T03:58:12Z |
| format | Article |
| id | doaj.art-7d0698d006754217ba0f980c14e25784 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-21T03:58:12Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-7d0698d006754217ba0f980c14e257842022-12-21T19:16:47ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01128e018282010.1371/journal.pone.0182820Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya.Ellen R RaffertyJanna M SchurerMichael B ArndtRobert K M ChoyEugenio L de HostosDavid ShoultzMarwa FaragCryptosporidium is a leading cause of pediatric diarrhea in resource-limited settings; yet, few studies report the health care costs or societal impacts of this protozoan parasite. Our study examined direct and indirect costs associated with symptomatic cryptosporidiosis in infants younger than 12 months in Kenya, Peru and Bangladesh. Inputs to the economic burden model, such as disease incidence, population size, health care seeking behaviour, hospital costs, travel costs, were extracted from peer-reviewed literature, government documents, and internationally validated statistical tools for each country. Indirect losses (i.e. caregiver income loss, mortality, and growth faltering) were also estimated. Our findings suggest that direct treatment costs per symptomatic cryptosporidiosis episode were highest in Kenya ($59.01), followed by Peru ($23.32), and Bangladesh ($7.62). The total annual economic impacts for the 0-11 month cohorts were highest in Peru ($41.5M; range $0.88-$599.3M), followed by Kenya ($37.4M; range $1.6-$804.5M) and Bangladesh ($9.6M, range $0.28-$91.5M). For all scenarios, indirect societal costs far outweighed direct treatment costs. These results highlight the critical need for innovative improvements to current prevention, diagnostic and treatment strategies available in resource poor settings, as well as the need for solutions that span multiple disciplines including food and water safety, sanitation and livestock production.http://europepmc.org/articles/PMC5568228?pdf=render |
| spellingShingle | Ellen R Rafferty Janna M Schurer Michael B Arndt Robert K M Choy Eugenio L de Hostos David Shoultz Marwa Farag Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya. PLoS ONE |
| title | Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya. |
| title_full | Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya. |
| title_fullStr | Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya. |
| title_full_unstemmed | Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya. |
| title_short | Pediatric cryptosporidiosis: An evaluation of health care and societal costs in Peru, Bangladesh and Kenya. |
| title_sort | pediatric cryptosporidiosis an evaluation of health care and societal costs in peru bangladesh and kenya |
| url | http://europepmc.org/articles/PMC5568228?pdf=render |
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