Oscillating Glucose Induces the Increase in Inflammatory Stress through Ninjurin-1 Up-Regulation and Stimulation of Transport Proteins in Human Endothelial Cells

Oscillating Glucose Induces the Increase in Inflammatory Stress through Ninjurin-1 Up-Regulation and Stimulation of Transport Proteins in Human Endothelial Cells

Clinical data implicate fluctuations of high levels of plasma glucose in cardiovascular diseases. Endothelial cells (EC) are the first cells of the vessel wall exposed to them. Our aim was to evaluate the effects of oscillating glucose (OG) on EC function and to decipher new molecular mechanisms inv...

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Bibliographic Details
Main Authors: Laura Toma, Gabriela M. Sanda, Camelia S. Stancu, Loredan S. Niculescu, Mina Raileanu, Anca V. Sima
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomolecules
Subjects:
endothelial cell dysfunction
inflammatory stress
oscillating glucose
oxidative stress
Ninjurin-1
transendothelial transport proteins
Online Access:https://www.mdpi.com/2218-273X/13/4/626

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