One-year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, India
Objectives The primary objective was to report the 1-year all-cause mortality among patients with stroke. The secondary objectives were (1) to report the mortality stratified by type of stroke and sex and (2) to report predictors of 1-year mortality among patients with stroke.Design A prospective co...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-11-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/11/e061258.full |
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| author | Manu Raj Remya Sudevan Damodaran Vasudevan Renjitha Bhaskaran Vivek Nambiar |
| author_facet | Manu Raj Remya Sudevan Damodaran Vasudevan Renjitha Bhaskaran Vivek Nambiar |
| author_sort | Manu Raj |
| collection | DOAJ |
| description | Objectives The primary objective was to report the 1-year all-cause mortality among patients with stroke. The secondary objectives were (1) to report the mortality stratified by type of stroke and sex and (2) to report predictors of 1-year mortality among patients with stroke.Design A prospective cohort study.Setting Institutional–stroke care unit of a tertiary care hospitalParticipants Patients who were treated in the study institution during 2016–2020 for acute stroke and were followed up for a period of 1 year after stroke in the same institution.Main outcome measures The main outcome measures were the mortality proportion of any stroke and first ever stroke cohorts at select time points, including in-hospital stay, along with 2 weeks, 2 months, 6 months and 1 year after index stroke. The secondary outcomes were (1) mortality proportions stratified by sex and type of stroke and (2) predictors of 1-year mortality for any stroke and first ever stroke.Results We recruited a total of 1336 patients. The mean age of participants was 61.6 years (13.5 years). The mortality figures for 2 weeks, 2 months, 6 months and 12 months after discharge were 79 (5.9%), 88 (6.7%), 101 (7.6%) and 114 (8.5%), respectively, in the full cohort. The in-hospital mortality was 45 (3.4%). The adjusted analysis revealed 3 predictors for 1-year mortality after first ever stroke—age, pre-treatment National Institutes of Health Stroke Scale (NIHSS) score and Modified Rankin Scale (mRS) score at baseline. The same for the full cohort had only two predictors—age and pre-treatment NIHSS score.Conclusion Mortality of stroke at 1-year follow-up in the study population is low in comparison to several studies published earlier. The predictors of 1-year mortality after stroke included age, NIHSS score at baseline and mRS score at baseline. |
| first_indexed | 2024-04-11T15:05:05Z |
| format | Article |
| id | doaj.art-7d1424c537de443185806068a48ae2da |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-04-11T15:05:05Z |
| publishDate | 2022-11-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-7d1424c537de443185806068a48ae2da2022-12-22T04:16:49ZengBMJ Publishing GroupBMJ Open2044-60552022-11-01121110.1136/bmjopen-2022-061258One-year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, IndiaManu Raj0Remya Sudevan1Damodaran Vasudevan2Renjitha Bhaskaran3Vivek Nambiar4Pediatrics & Pediatric Cardiology, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India4 Medical Research, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, IndiaDepartment of Health Sciences Research, Amrita Institute of Medical Sciences & Research Centre, Amrita Vishwa Vidyapeetham, Kochi, IndiaAmrita Institute Of Medical Sciences And Research Centre, Kochi, India1Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, CanadaObjectives The primary objective was to report the 1-year all-cause mortality among patients with stroke. The secondary objectives were (1) to report the mortality stratified by type of stroke and sex and (2) to report predictors of 1-year mortality among patients with stroke.Design A prospective cohort study.Setting Institutional–stroke care unit of a tertiary care hospitalParticipants Patients who were treated in the study institution during 2016–2020 for acute stroke and were followed up for a period of 1 year after stroke in the same institution.Main outcome measures The main outcome measures were the mortality proportion of any stroke and first ever stroke cohorts at select time points, including in-hospital stay, along with 2 weeks, 2 months, 6 months and 1 year after index stroke. The secondary outcomes were (1) mortality proportions stratified by sex and type of stroke and (2) predictors of 1-year mortality for any stroke and first ever stroke.Results We recruited a total of 1336 patients. The mean age of participants was 61.6 years (13.5 years). The mortality figures for 2 weeks, 2 months, 6 months and 12 months after discharge were 79 (5.9%), 88 (6.7%), 101 (7.6%) and 114 (8.5%), respectively, in the full cohort. The in-hospital mortality was 45 (3.4%). The adjusted analysis revealed 3 predictors for 1-year mortality after first ever stroke—age, pre-treatment National Institutes of Health Stroke Scale (NIHSS) score and Modified Rankin Scale (mRS) score at baseline. The same for the full cohort had only two predictors—age and pre-treatment NIHSS score.Conclusion Mortality of stroke at 1-year follow-up in the study population is low in comparison to several studies published earlier. The predictors of 1-year mortality after stroke included age, NIHSS score at baseline and mRS score at baseline.https://bmjopen.bmj.com/content/12/11/e061258.full |
| spellingShingle | Manu Raj Remya Sudevan Damodaran Vasudevan Renjitha Bhaskaran Vivek Nambiar One-year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, India BMJ Open |
| title | One-year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, India |
| title_full | One-year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, India |
| title_fullStr | One-year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, India |
| title_full_unstemmed | One-year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, India |
| title_short | One-year mortality after acute stroke: a prospective cohort study from a comprehensive stroke care centre, Kerala, India |
| title_sort | one year mortality after acute stroke a prospective cohort study from a comprehensive stroke care centre kerala india |
| url | https://bmjopen.bmj.com/content/12/11/e061258.full |
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