Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experience
Abstract Background The incidence of papillary thyroid microcarcinoma (PTMC) is increasing; however, it is not clear whether this reflects an increase in the incidence of incidental or in that of non-incidentally (presurgically) discovered PTMC (IPTMC vs. NIPTMC). We assessed the incidence of IPTMC...
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| Format: | Article |
| Language: | English |
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BMC
2018-10-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12957-018-1501-8 |
| _version_ | 1818023065668288512 |
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| author | Krzysztof Kaliszewski Agnieszka Zubkiewicz-Kucharska Paweł Kiełb Jerzy Maksymowicz Aleksander Krawczyk Otto Krawiec |
| author_facet | Krzysztof Kaliszewski Agnieszka Zubkiewicz-Kucharska Paweł Kiełb Jerzy Maksymowicz Aleksander Krawczyk Otto Krawiec |
| author_sort | Krzysztof Kaliszewski |
| collection | DOAJ |
| description | Abstract Background The incidence of papillary thyroid microcarcinoma (PTMC) is increasing; however, it is not clear whether this reflects an increase in the incidence of incidental or in that of non-incidentally (presurgically) discovered PTMC (IPTMC vs. NIPTMC). We assessed the incidence of IPTMC and NIPTMC over the past 9 years, to discern whether the increase in PTMC incidence is due to improved diagnostics or to a real increase in the incidence. Methods We performed a retrospective chart review of 4327 patients who were consecutively admitted to and surgically treated for thyroid pathology at a single institution. As a main presurgical diagnostic test, all patients underwent ultrasound-guided fine-needle aspiration biopsy (UG-FNAB). The analyzed time frame was divided into three equal periods (I: 2008–2010, II: 2011–2013, III: 2014–2016), and IPTMCs and NIPTMCs were assessed and compared in each period. Results We evaluated 393 (9.08%) patients with thyroid malignancy, of which 156 (3.60% of all thyroid tumors [TTs]; 39.69% of all thyroid cancers [TCs]) were diagnosed as PTMC. The prevalence of NIPTMC among all TCs increased from 16.66% in 2008 to 33.75% in 2016, while that of IPTMC decreased from 20.83% in 2008 to 13.75% in 2016. The incidence rates of NIPTMC and IPTMC in period III differed statistically significantly (p < 0.0001). The prevalence rate of NIPTMC in period III was higher than that in period II, yet comparable to that in period I (p = 0.0014; p = 0.2804, respectively). Conclusions The prevalence of NIPTMC, rather than that of IPTMC, is escalating; this may be due to better presurgical diagnosis. |
| first_indexed | 2024-12-10T03:38:24Z |
| format | Article |
| id | doaj.art-7d17248cb960420eba14c68c37436d70 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-10T03:38:24Z |
| publishDate | 2018-10-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-7d17248cb960420eba14c68c37436d702022-12-22T02:03:39ZengBMCWorld Journal of Surgical Oncology1477-78192018-10-011611610.1186/s12957-018-1501-8Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experienceKrzysztof Kaliszewski0Agnieszka Zubkiewicz-Kucharska1Paweł Kiełb2Jerzy Maksymowicz3Aleksander Krawczyk4Otto Krawiec5First Department and Clinic of General, Gastroenterological, and Endocrine Surgery, Wroclaw Medical UniversityDepartment of Endocrinology and Diabetology for Children and Adolescents, Wroclaw Medical UniversityFirst Department and Clinic of General, Gastroenterological, and Endocrine Surgery, Wroclaw Medical UniversityFirst Department and Clinic of General, Gastroenterological, and Endocrine Surgery, Wroclaw Medical UniversityFirst Department and Clinic of General, Gastroenterological, and Endocrine Surgery, Wroclaw Medical UniversityFirst Department and Clinic of General, Gastroenterological, and Endocrine Surgery, Wroclaw Medical UniversityAbstract Background The incidence of papillary thyroid microcarcinoma (PTMC) is increasing; however, it is not clear whether this reflects an increase in the incidence of incidental or in that of non-incidentally (presurgically) discovered PTMC (IPTMC vs. NIPTMC). We assessed the incidence of IPTMC and NIPTMC over the past 9 years, to discern whether the increase in PTMC incidence is due to improved diagnostics or to a real increase in the incidence. Methods We performed a retrospective chart review of 4327 patients who were consecutively admitted to and surgically treated for thyroid pathology at a single institution. As a main presurgical diagnostic test, all patients underwent ultrasound-guided fine-needle aspiration biopsy (UG-FNAB). The analyzed time frame was divided into three equal periods (I: 2008–2010, II: 2011–2013, III: 2014–2016), and IPTMCs and NIPTMCs were assessed and compared in each period. Results We evaluated 393 (9.08%) patients with thyroid malignancy, of which 156 (3.60% of all thyroid tumors [TTs]; 39.69% of all thyroid cancers [TCs]) were diagnosed as PTMC. The prevalence of NIPTMC among all TCs increased from 16.66% in 2008 to 33.75% in 2016, while that of IPTMC decreased from 20.83% in 2008 to 13.75% in 2016. The incidence rates of NIPTMC and IPTMC in period III differed statistically significantly (p < 0.0001). The prevalence rate of NIPTMC in period III was higher than that in period II, yet comparable to that in period I (p = 0.0014; p = 0.2804, respectively). Conclusions The prevalence of NIPTMC, rather than that of IPTMC, is escalating; this may be due to better presurgical diagnosis.http://link.springer.com/article/10.1186/s12957-018-1501-8IncidentalNon-incidentalPapillary thyroid microcarcinoma |
| spellingShingle | Krzysztof Kaliszewski Agnieszka Zubkiewicz-Kucharska Paweł Kiełb Jerzy Maksymowicz Aleksander Krawczyk Otto Krawiec Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experience World Journal of Surgical Oncology Incidental Non-incidental Papillary thyroid microcarcinoma |
| title | Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experience |
| title_full | Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experience |
| title_fullStr | Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experience |
| title_full_unstemmed | Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experience |
| title_short | Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experience |
| title_sort | comparison of the prevalence of incidental and non incidental papillary thyroid microcarcinoma during 2008 2016 a single center experience |
| topic | Incidental Non-incidental Papillary thyroid microcarcinoma |
| url | http://link.springer.com/article/10.1186/s12957-018-1501-8 |
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