Pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosis
Abstract Renal vein thrombosis (RVT) is a rare vascular complication that occurs after renal transplantation and usually results in irreversible kidney damage and graft loss. We report the case of a patient who underwent right iliac fossa allogeneic kidney transplantation and developed RVT combined...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-10-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-44514-8 |
| _version_ | 1797452854938566656 |
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| author | Shao-Jie Wu Chi Zhang Min Wu Dan-dan Ruan Yan-ping Zhang Bin Lin Yi Tang Xin Chen Chen Wang Hong-hong Pan Qing-guo Zhu Jie-wei Luo Lie-fu Ye Zhu-ting Fang |
| author_facet | Shao-Jie Wu Chi Zhang Min Wu Dan-dan Ruan Yan-ping Zhang Bin Lin Yi Tang Xin Chen Chen Wang Hong-hong Pan Qing-guo Zhu Jie-wei Luo Lie-fu Ye Zhu-ting Fang |
| author_sort | Shao-Jie Wu |
| collection | DOAJ |
| description | Abstract Renal vein thrombosis (RVT) is a rare vascular complication that occurs after renal transplantation and usually results in irreversible kidney damage and graft loss. We report the case of a patient who underwent right iliac fossa allogeneic kidney transplantation and developed RVT combined with ipsilateral thrombosis from the popliteal to the femoral veins, with extension to the common iliac veins, 4 months after transplantation. Under unfractionated heparin anticoagulation, an Aegisy (Life Tech Scientific Co., Ltd., Shenzhen, China) vena cava filter was placed to prevent pulmonary embolism. Percutaneous mechanical thrombectomy combined with balloon angioplasty was performed to aspirate the thrombus and successfully dilate the narrow venous lumen. The patient’s renal function was restored postoperatively. Ultrasonography showed the allograft and ipsilateral lower extremity deep veins to be fluent and patent. To conclude, in patients with RVT after renal transplantation, percutaneous mechanical thrombectomy in conjunction with balloon angioplasty can be performed with desirable outcomes and no severe adverse effects. This method reduces the risk of bleeding from exposure to systemic intravenous thrombolysis and avoids surgery-associated trauma. |
| first_indexed | 2024-03-09T15:13:44Z |
| format | Article |
| id | doaj.art-7d197e5f2f1e4d949e92b418da1b7d8d |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-09T15:13:44Z |
| publishDate | 2023-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-7d197e5f2f1e4d949e92b418da1b7d8d2023-11-26T13:11:35ZengNature PortfolioScientific Reports2045-23222023-10-011311810.1038/s41598-023-44514-8Pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosisShao-Jie Wu0Chi Zhang1Min Wu2Dan-dan Ruan3Yan-ping Zhang4Bin Lin5Yi Tang6Xin Chen7Chen Wang8Hong-hong Pan9Qing-guo Zhu10Jie-wei Luo11Lie-fu Ye12Zhu-ting Fang13Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityFujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical UniversityAbstract Renal vein thrombosis (RVT) is a rare vascular complication that occurs after renal transplantation and usually results in irreversible kidney damage and graft loss. We report the case of a patient who underwent right iliac fossa allogeneic kidney transplantation and developed RVT combined with ipsilateral thrombosis from the popliteal to the femoral veins, with extension to the common iliac veins, 4 months after transplantation. Under unfractionated heparin anticoagulation, an Aegisy (Life Tech Scientific Co., Ltd., Shenzhen, China) vena cava filter was placed to prevent pulmonary embolism. Percutaneous mechanical thrombectomy combined with balloon angioplasty was performed to aspirate the thrombus and successfully dilate the narrow venous lumen. The patient’s renal function was restored postoperatively. Ultrasonography showed the allograft and ipsilateral lower extremity deep veins to be fluent and patent. To conclude, in patients with RVT after renal transplantation, percutaneous mechanical thrombectomy in conjunction with balloon angioplasty can be performed with desirable outcomes and no severe adverse effects. This method reduces the risk of bleeding from exposure to systemic intravenous thrombolysis and avoids surgery-associated trauma.https://doi.org/10.1038/s41598-023-44514-8 |
| spellingShingle | Shao-Jie Wu Chi Zhang Min Wu Dan-dan Ruan Yan-ping Zhang Bin Lin Yi Tang Xin Chen Chen Wang Hong-hong Pan Qing-guo Zhu Jie-wei Luo Lie-fu Ye Zhu-ting Fang Pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosis Scientific Reports |
| title | Pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosis |
| title_full | Pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosis |
| title_fullStr | Pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosis |
| title_full_unstemmed | Pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosis |
| title_short | Pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosis |
| title_sort | pharmarcomechanical thrombectomy combined with transluminal balloon angioplasty for treating transplant renal vein thrombosis |
| url | https://doi.org/10.1038/s41598-023-44514-8 |
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