Evaluation of the Relationship Between Depression, Anxiety, and Stress with Hypertension: Results of a Health Study in Yazd, Iran

Background and Aim: Over the past few decades, different epidemiological studies have been conducted on the relationship between mental disorders and hypertension. However, conflicting results have been reported. This research aimed to evaluate the relationship between symptoms of depression, anxiet...

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Main Authors: Mohammad Khajeh, Masoud Mirzaei, Azadeh Nadjarzadeh
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-06-01
Series:Journal of Biostatistics and Epidemiology
Subjects:
Online Access:https://jbe.tums.ac.ir/index.php/jbe/article/view/311
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author Mohammad Khajeh
Masoud Mirzaei
Azadeh Nadjarzadeh
author_facet Mohammad Khajeh
Masoud Mirzaei
Azadeh Nadjarzadeh
author_sort Mohammad Khajeh
collection DOAJ
description Background and Aim: Over the past few decades, different epidemiological studies have been conducted on the relationship between mental disorders and hypertension. However, conflicting results have been reported. This research aimed to evaluate the relationship between symptoms of depression, anxiety and stress with hypertension in a large population. Materials and Methods: This cross-sectional analytic study was conducted using the results of in Yazd Health Study, Iran (N=9340). In addition, DASS-21 questionnaire was asked from the participants to assess depression, anxiety, and stress. Moreover, logistic regression was used to evaluate the relationship between symptoms of depression, anxiety and stress with hypertension. Results: A negative association was observed between systolic and diastolic blood pressure and symptoms of depression, anxiety, and stress, which were independent from other variables. Regarding systolic blood pressure, a significant and reverse relationship was found in individuals with moderate stress (OR: 0.81, 95% CI: 0.69-0.95) and mild depression (OR: 0.82, 95% CI: 0.68-0.99). In terms of diastolic blood pressure, subjects with moderate stress had a lower blood pressure, compared to healthy individuals (OR: 0.86, 95% CI: 0.750.99). Furthermore, participants with depression had a lower chance of being diagnosed with hypertension, compared to healthy individuals. Conclusion: The present research did not confirm the previous assumptions about the relationship between depression, anxiety and stress with hypertension. Our findings showed that symptoms of depression, anxiety, and stress are correlated with a low blood pressure.
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spelling doaj.art-7d1feb578c6247d3b5d1347ae756f9382022-12-21T20:19:27ZengTehran University of Medical SciencesJournal of Biostatistics and Epidemiology2383-41962383-420X2020-06-015310.18502/jbe.v5i3.3621Evaluation of the Relationship Between Depression, Anxiety, and Stress with Hypertension: Results of a Health Study in Yazd, IranMohammad Khajeh0Masoud Mirzaei1Azadeh Nadjarzadeh2Department of Biostatistics and Epidemiology, School of Public Health, Esfahan University of Medical Sciences, Esfahan- IranYazd Cardiovascular Research Centre, Shahid Sadoughi University of Medical Sciences, Yazd-IranNutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.Background and Aim: Over the past few decades, different epidemiological studies have been conducted on the relationship between mental disorders and hypertension. However, conflicting results have been reported. This research aimed to evaluate the relationship between symptoms of depression, anxiety and stress with hypertension in a large population. Materials and Methods: This cross-sectional analytic study was conducted using the results of in Yazd Health Study, Iran (N=9340). In addition, DASS-21 questionnaire was asked from the participants to assess depression, anxiety, and stress. Moreover, logistic regression was used to evaluate the relationship between symptoms of depression, anxiety and stress with hypertension. Results: A negative association was observed between systolic and diastolic blood pressure and symptoms of depression, anxiety, and stress, which were independent from other variables. Regarding systolic blood pressure, a significant and reverse relationship was found in individuals with moderate stress (OR: 0.81, 95% CI: 0.69-0.95) and mild depression (OR: 0.82, 95% CI: 0.68-0.99). In terms of diastolic blood pressure, subjects with moderate stress had a lower blood pressure, compared to healthy individuals (OR: 0.86, 95% CI: 0.750.99). Furthermore, participants with depression had a lower chance of being diagnosed with hypertension, compared to healthy individuals. Conclusion: The present research did not confirm the previous assumptions about the relationship between depression, anxiety and stress with hypertension. Our findings showed that symptoms of depression, anxiety, and stress are correlated with a low blood pressure.https://jbe.tums.ac.ir/index.php/jbe/article/view/311Hypertension;Depression;Anxiety;Stress
spellingShingle Mohammad Khajeh
Masoud Mirzaei
Azadeh Nadjarzadeh
Evaluation of the Relationship Between Depression, Anxiety, and Stress with Hypertension: Results of a Health Study in Yazd, Iran
Journal of Biostatistics and Epidemiology
Hypertension;
Depression;
Anxiety;
Stress
title Evaluation of the Relationship Between Depression, Anxiety, and Stress with Hypertension: Results of a Health Study in Yazd, Iran
title_full Evaluation of the Relationship Between Depression, Anxiety, and Stress with Hypertension: Results of a Health Study in Yazd, Iran
title_fullStr Evaluation of the Relationship Between Depression, Anxiety, and Stress with Hypertension: Results of a Health Study in Yazd, Iran
title_full_unstemmed Evaluation of the Relationship Between Depression, Anxiety, and Stress with Hypertension: Results of a Health Study in Yazd, Iran
title_short Evaluation of the Relationship Between Depression, Anxiety, and Stress with Hypertension: Results of a Health Study in Yazd, Iran
title_sort evaluation of the relationship between depression anxiety and stress with hypertension results of a health study in yazd iran
topic Hypertension;
Depression;
Anxiety;
Stress
url https://jbe.tums.ac.ir/index.php/jbe/article/view/311
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