Prenatal Invasive Diagnosis with Quantitative Fluorescent PCR
Purpose: To develop the method of prenatal invasive diagnosis and compare it abilities with traditional genetic cytological examination.Materials and Methods: There was conducted prenatal fetal invasive diagnosis of 366 pregnant women. Depending on the pregnancy age and genetic indications the chori...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2011-06-01
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| Series: | Медицинский вестник Юга России |
| Subjects: | |
| Online Access: | https://www.medicalherald.ru/jour/article/view/1204 |
| _version_ | 1811179480728731648 |
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| author | V. V. Avrutskaja N. V. Kriventsova R. A. Shokarev V. S. Gimbut S. Y. Kriger |
| author_facet | V. V. Avrutskaja N. V. Kriventsova R. A. Shokarev V. S. Gimbut S. Y. Kriger |
| author_sort | V. V. Avrutskaja |
| collection | DOAJ |
| description | Purpose: To develop the method of prenatal invasive diagnosis and compare it abilities with traditional genetic cytological examination.Materials and Methods: There was conducted prenatal fetal invasive diagnosis of 366 pregnant women. Depending on the pregnancy age and genetic indications the chorionic villus sampling, cordocentesis and amniocentesis were carried.Results: The obtained samples was treated with QF-PCR and it results was verified by standard karyotyping. In all cases, the differences of the two methods was not observed.Summary: It was shown the technique of quantitative fluorescent polymerase chain reaction (QF-PCR) has advantages over the standard cytologic examination and reduces analysis duration and increases the number of patients. |
| first_indexed | 2024-04-11T06:34:56Z |
| format | Article |
| id | doaj.art-7d203d072ba74d8982720f7f93370057 |
| institution | Directory Open Access Journal |
| issn | 2219-8075 2618-7876 |
| language | English |
| last_indexed | 2024-04-11T06:34:56Z |
| publishDate | 2011-06-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Медицинский вестник Юга России |
| spelling | doaj.art-7d203d072ba74d8982720f7f933700572022-12-22T04:39:51ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762011-06-01026062691Prenatal Invasive Diagnosis with Quantitative Fluorescent PCRV. V. Avrutskaja0N. V. Kriventsova1R. A. Shokarev2V. S. Gimbut3S. Y. Kriger4Rostov Scientific Research Institute of Obstetrics and PediatricsRostov Scientific Research Institute of Obstetrics and PediatricsRostov Scientific Research Institute of Obstetrics and PediatricsRostov Scientific Research Institute of Obstetrics and PediatricsRostov Scientific Research Institute of Obstetrics and PediatricsPurpose: To develop the method of prenatal invasive diagnosis and compare it abilities with traditional genetic cytological examination.Materials and Methods: There was conducted prenatal fetal invasive diagnosis of 366 pregnant women. Depending on the pregnancy age and genetic indications the chorionic villus sampling, cordocentesis and amniocentesis were carried.Results: The obtained samples was treated with QF-PCR and it results was verified by standard karyotyping. In all cases, the differences of the two methods was not observed.Summary: It was shown the technique of quantitative fluorescent polymerase chain reaction (QF-PCR) has advantages over the standard cytologic examination and reduces analysis duration and increases the number of patients.https://www.medicalherald.ru/jour/article/view/1204prenatal diagnosischromosome diseasesquantitative polymerase-chain reaction |
| spellingShingle | V. V. Avrutskaja N. V. Kriventsova R. A. Shokarev V. S. Gimbut S. Y. Kriger Prenatal Invasive Diagnosis with Quantitative Fluorescent PCR Медицинский вестник Юга России prenatal diagnosis chromosome diseases quantitative polymerase-chain reaction |
| title | Prenatal Invasive Diagnosis with Quantitative Fluorescent PCR |
| title_full | Prenatal Invasive Diagnosis with Quantitative Fluorescent PCR |
| title_fullStr | Prenatal Invasive Diagnosis with Quantitative Fluorescent PCR |
| title_full_unstemmed | Prenatal Invasive Diagnosis with Quantitative Fluorescent PCR |
| title_short | Prenatal Invasive Diagnosis with Quantitative Fluorescent PCR |
| title_sort | prenatal invasive diagnosis with quantitative fluorescent pcr |
| topic | prenatal diagnosis chromosome diseases quantitative polymerase-chain reaction |
| url | https://www.medicalherald.ru/jour/article/view/1204 |
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