Research Progress in the Treatment of Autism Spectrum Disorder with Fecal Microbiota Transplantation

Autism spectrum disorder (ASD), a neurodevelopmental disorder during early childhood, currently has no effective treatment. The prevalence of ASD has been increasing, which brings a heavy burden to the family of the patients and the society. Children with ASD are accompanied by gastrointestinal symp...

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Main Authors: LI Xiaoyan, XU Xinjie, LUO Xin, YOU Xin
Format: Article
Language:zho
Published: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2022-09-01
Series:Xiehe Yixue Zazhi
Subjects:
Online Access:https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0301
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author LI Xiaoyan
XU Xinjie
LUO Xin
YOU Xin
author_facet LI Xiaoyan
XU Xinjie
LUO Xin
YOU Xin
author_sort LI Xiaoyan
collection DOAJ
description Autism spectrum disorder (ASD), a neurodevelopmental disorder during early childhood, currently has no effective treatment. The prevalence of ASD has been increasing, which brings a heavy burden to the family of the patients and the society. Children with ASD are accompanied by gastrointestinal symptoms and have an imbalance of intestinal microbiota. Fecal microbiota transplantation (FMT) can improve autism-related symptoms in children with ASD. This review aims to summarize the research progress of FMT for treating ASD to provide a novel strategy for this untreatable disease.
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spelling doaj.art-7d22163e60674b30a65ae4b67cfb5dc92022-12-22T03:38:30ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812022-09-0113575375910.12290/xhyxzz.2022-0301Research Progress in the Treatment of Autism Spectrum Disorder with Fecal Microbiota TransplantationLI Xiaoyan0XU Xinjie1LUO Xin2YOU Xin3Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaMedical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaAutism spectrum disorder (ASD), a neurodevelopmental disorder during early childhood, currently has no effective treatment. The prevalence of ASD has been increasing, which brings a heavy burden to the family of the patients and the society. Children with ASD are accompanied by gastrointestinal symptoms and have an imbalance of intestinal microbiota. Fecal microbiota transplantation (FMT) can improve autism-related symptoms in children with ASD. This review aims to summarize the research progress of FMT for treating ASD to provide a novel strategy for this untreatable disease.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0301autismfecal microbiota transplantationdevelopmental disordersintestinal flora
spellingShingle LI Xiaoyan
XU Xinjie
LUO Xin
YOU Xin
Research Progress in the Treatment of Autism Spectrum Disorder with Fecal Microbiota Transplantation
Xiehe Yixue Zazhi
autism
fecal microbiota transplantation
developmental disorders
intestinal flora
title Research Progress in the Treatment of Autism Spectrum Disorder with Fecal Microbiota Transplantation
title_full Research Progress in the Treatment of Autism Spectrum Disorder with Fecal Microbiota Transplantation
title_fullStr Research Progress in the Treatment of Autism Spectrum Disorder with Fecal Microbiota Transplantation
title_full_unstemmed Research Progress in the Treatment of Autism Spectrum Disorder with Fecal Microbiota Transplantation
title_short Research Progress in the Treatment of Autism Spectrum Disorder with Fecal Microbiota Transplantation
title_sort research progress in the treatment of autism spectrum disorder with fecal microbiota transplantation
topic autism
fecal microbiota transplantation
developmental disorders
intestinal flora
url https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0301
work_keys_str_mv AT lixiaoyan researchprogressinthetreatmentofautismspectrumdisorderwithfecalmicrobiotatransplantation
AT xuxinjie researchprogressinthetreatmentofautismspectrumdisorderwithfecalmicrobiotatransplantation
AT luoxin researchprogressinthetreatmentofautismspectrumdisorderwithfecalmicrobiotatransplantation
AT youxin researchprogressinthetreatmentofautismspectrumdisorderwithfecalmicrobiotatransplantation