Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis

Introduction Childhood vaccine delivery services in the low- and middle-income countries (LMIC) are struggling to reach every child with lifesaving vaccines. Short message service (SMS) reminders have demonstrated positive impact on a number of attrition-prone healthcare delivery services. We aimed...

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Main Authors: Yubraj Acharya, Paul Eze, Lucky Osaheni Lawani
Format: Article
Language:English
Published: BMJ Publishing Group 2021-07-01
Series:BMJ Global Health
Online Access:https://gh.bmj.com/content/6/7/e005035.full
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author Yubraj Acharya
Paul Eze
Lucky Osaheni Lawani
author_facet Yubraj Acharya
Paul Eze
Lucky Osaheni Lawani
author_sort Yubraj Acharya
collection DOAJ
description Introduction Childhood vaccine delivery services in the low- and middle-income countries (LMIC) are struggling to reach every child with lifesaving vaccines. Short message service (SMS) reminders have demonstrated positive impact on a number of attrition-prone healthcare delivery services. We aimed to evaluate the effectiveness of SMS reminders in improving immunisation coverage and timeliness in LMICs.Methods PubMed, Embase, Scopus, Cochrane CENTRAL, CINAHL, CNKI, PsycINFO and Web of Science including grey literatures and Google Scholar were systematically searched for randomised controlled trials (RCTs) and non-RCTs that evaluated the effect of SMS reminders on childhood immunisation and timeliness in LMICs. Risk of bias was assessed using the Cochrane Risk of Bias 2.0 assessment tool for RCTs and Cochrane Risk of Bias in Non-randomised Studies of Interventions tool for non-RCTs. Meta-analysis was conducted using random-effects models to generate pooled estimates of risk ratio (RR).Results 18 studies, 13 RCTs and 5 non-RCTs involving 32 712 infants (17 135 in intervention groups and 15 577 in control groups) from 11 LMICs met inclusion criteria. Pooled estimates showed that SMS reminders significantly improved childhood immunisation coverage (RR=1.16; 95% CI: 1.10 to 1.21; I2=90.4%). Meta-analysis of 12 included studies involving 25 257 infants showed that SMS reminders significantly improved timely receipt of childhood vaccines (RR=1.21; 95% CI: 1.12 to 1.30; I2=87.3%). Subgroup analysis showed that SMS reminders are significantly more effective in raising childhood immunisation coverage in lower middle-income and low-income countries than in upper middle-income countries (p<0.001) and sending more than two SMS reminders significantly improves timely receipt of childhood vaccines than one or two SMS reminders (p=0.040).Conclusion Current evidence from LMICs, although with significant heterogeneity, suggests that SMS reminders can contribute to achieving high and timely childhood immunisation coverage.PROSPERO registration number CRD42021225843.
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spelling doaj.art-7d25832f6af049b9ac002894f5ab2f392022-12-21T19:11:57ZengBMJ Publishing GroupBMJ Global Health2059-79082021-07-016710.1136/bmjgh-2021-005035Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysisYubraj Acharya0Paul Eze1Lucky Osaheni Lawani2Department of Health Policy and Administration, Pennsylvania State University, University Park, Pennsylvania, USADepartment of Health Policy and Administration, Pennsylvania State University, University Park, Pennsylvania, USAInstitute of Health Policy, Management & Evaluation, University of Toronto, Toronto, Ontario, CanadaIntroduction Childhood vaccine delivery services in the low- and middle-income countries (LMIC) are struggling to reach every child with lifesaving vaccines. Short message service (SMS) reminders have demonstrated positive impact on a number of attrition-prone healthcare delivery services. We aimed to evaluate the effectiveness of SMS reminders in improving immunisation coverage and timeliness in LMICs.Methods PubMed, Embase, Scopus, Cochrane CENTRAL, CINAHL, CNKI, PsycINFO and Web of Science including grey literatures and Google Scholar were systematically searched for randomised controlled trials (RCTs) and non-RCTs that evaluated the effect of SMS reminders on childhood immunisation and timeliness in LMICs. Risk of bias was assessed using the Cochrane Risk of Bias 2.0 assessment tool for RCTs and Cochrane Risk of Bias in Non-randomised Studies of Interventions tool for non-RCTs. Meta-analysis was conducted using random-effects models to generate pooled estimates of risk ratio (RR).Results 18 studies, 13 RCTs and 5 non-RCTs involving 32 712 infants (17 135 in intervention groups and 15 577 in control groups) from 11 LMICs met inclusion criteria. Pooled estimates showed that SMS reminders significantly improved childhood immunisation coverage (RR=1.16; 95% CI: 1.10 to 1.21; I2=90.4%). Meta-analysis of 12 included studies involving 25 257 infants showed that SMS reminders significantly improved timely receipt of childhood vaccines (RR=1.21; 95% CI: 1.12 to 1.30; I2=87.3%). Subgroup analysis showed that SMS reminders are significantly more effective in raising childhood immunisation coverage in lower middle-income and low-income countries than in upper middle-income countries (p<0.001) and sending more than two SMS reminders significantly improves timely receipt of childhood vaccines than one or two SMS reminders (p=0.040).Conclusion Current evidence from LMICs, although with significant heterogeneity, suggests that SMS reminders can contribute to achieving high and timely childhood immunisation coverage.PROSPERO registration number CRD42021225843.https://gh.bmj.com/content/6/7/e005035.full
spellingShingle Yubraj Acharya
Paul Eze
Lucky Osaheni Lawani
Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis
BMJ Global Health
title Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis
title_full Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis
title_fullStr Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis
title_full_unstemmed Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis
title_short Short message service (SMS) reminders for childhood immunisation in low-income and middle-income countries: a systematic review and meta-analysis
title_sort short message service sms reminders for childhood immunisation in low income and middle income countries a systematic review and meta analysis
url https://gh.bmj.com/content/6/7/e005035.full
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AT luckyosahenilawani shortmessageservicesmsremindersforchildhoodimmunisationinlowincomeandmiddleincomecountriesasystematicreviewandmetaanalysis