Atrophy of the Posterior Subiculum Is Associated with Memory Impairment, Tau- and Aβ Pathology in Non-demented Individuals

Atrophy of the Posterior Subiculum Is Associated with Memory Impairment, Tau- and Aβ Pathology in Non-demented Individuals

Alzheimer’s disease (AD) is associated with atrophy of the cornu ammonis (CA) 1 and the subiculum subfield of the hippocampus (HC), and with deficits in episodic memory and spatial orientation. These deficits are mainly associated with the functionality of the posterior HC. We therefore hypothesized...

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Bibliographic Details
Main Authors: Olof Lindberg, Gustav Mårtensson, Erik Stomrud, Sebastian Palmqvist, Lars-Olof Wahlund, Eric Westman, Oskar Hansson
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
hippocampus subfield
beta amyloid
subjective cognitive decline
mild cognitive impairment
preclinical AD
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00306/full

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