Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study
Background: Identification of predictors for atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) can lead to better long-term results. Our aim was to investigate the association between novel CT imaging markers reflecting the severity of coronary atherosclerosis and the risk of...
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MDPI AG
2023-09-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/9/1891 |
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| author | Lehel László Bordi Theodora Benedek István Kovács Diana Opincariu Emese Márton Zsolt Parajkó Renáta Gerculy Imre Benedek |
| author_facet | Lehel László Bordi Theodora Benedek István Kovács Diana Opincariu Emese Márton Zsolt Parajkó Renáta Gerculy Imre Benedek |
| author_sort | Lehel László Bordi |
| collection | DOAJ |
| description | Background: Identification of predictors for atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) can lead to better long-term results. Our aim was to investigate the association between novel CT imaging markers reflecting the severity of coronary atherosclerosis and the risk of recurrence following PVI. Methods: This study included 80 patients with paroxysmal/persistent AF who underwent PVI. The patients were divided into two groups: Group 1–23 patients with recurrence and Group 2–57 patients without recurrence. Results: Patients with recurrence presented with a more enlarged left atrial diameter and reduced left ventricle EF, as assessed by echocardiography. Elevated calcium scores and right coronary artery (RCA) stenosis were correlated with a higher risk of AF recurrence (25.38 ± 4.1% vs. 9.76 ± 2.32%, <i>p</i> = 0.001). Patients with AF recurrence presented a higher left atrial volume index (LAVI) (61.38 ± 11.12 mm<sup>3</sup>/m<sup>2</sup> vs. 46.34 ± 12.27 mm<sup>3</sup>/m<sup>2</sup>, <i>p</i> < 0.0001). The bi-atrial volume index (BAVI) was similarly higher in the AF recurrence group (98.23 ± 14.44 mm<sup>3</sup>/m<sup>2</sup> vs. 76.48 ± 17.61 mm<sup>3</sup>/m<sup>2</sup>, <i>p</i> < 0.0001). Increased EAT volumes located around the LA (EAT-LA) were correlated with recurrence (25.55 ± 6.37 vs. 15.54 ± 8.44, <i>p</i> < 0.0001). Conclusions: RCA stenosis, together with atrial volumes and EAT-AS evaluated by CCTA, is associated with the risk of AF recurrence following PVI. |
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| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-10T22:33:06Z |
| publishDate | 2023-09-01 |
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| spelling | doaj.art-7d2c5c8387f04fc9a12556a78c6260212023-11-19T11:37:44ZengMDPI AGLife2075-17292023-09-01139189110.3390/life13091891Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality StudyLehel László Bordi0Theodora Benedek1István Kovács2Diana Opincariu3Emese Márton4Zsolt Parajkó5Renáta Gerculy6Imre Benedek7Clinic of Cardiology, Mures, County Emergency Clinical Hospital, 540142 Targu Mures, RomaniaClinic of Cardiology, Mures, County Emergency Clinical Hospital, 540142 Targu Mures, RomaniaClinic of Cardiology, Mures, County Emergency Clinical Hospital, 540142 Targu Mures, RomaniaCenter of Advanced Research in Multimodality Cardiac Imaging, CardioMed Medical Center, 540124 Targu Mures, RomaniaClinic of Cardiology, Mures, County Emergency Clinical Hospital, 540142 Targu Mures, RomaniaClinic of Cardiology, Mures, County Emergency Clinical Hospital, 540142 Targu Mures, RomaniaClinic of Cardiology, Mures, County Emergency Clinical Hospital, 540142 Targu Mures, RomaniaClinic of Cardiology, Mures, County Emergency Clinical Hospital, 540142 Targu Mures, RomaniaBackground: Identification of predictors for atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) can lead to better long-term results. Our aim was to investigate the association between novel CT imaging markers reflecting the severity of coronary atherosclerosis and the risk of recurrence following PVI. Methods: This study included 80 patients with paroxysmal/persistent AF who underwent PVI. The patients were divided into two groups: Group 1–23 patients with recurrence and Group 2–57 patients without recurrence. Results: Patients with recurrence presented with a more enlarged left atrial diameter and reduced left ventricle EF, as assessed by echocardiography. Elevated calcium scores and right coronary artery (RCA) stenosis were correlated with a higher risk of AF recurrence (25.38 ± 4.1% vs. 9.76 ± 2.32%, <i>p</i> = 0.001). Patients with AF recurrence presented a higher left atrial volume index (LAVI) (61.38 ± 11.12 mm<sup>3</sup>/m<sup>2</sup> vs. 46.34 ± 12.27 mm<sup>3</sup>/m<sup>2</sup>, <i>p</i> < 0.0001). The bi-atrial volume index (BAVI) was similarly higher in the AF recurrence group (98.23 ± 14.44 mm<sup>3</sup>/m<sup>2</sup> vs. 76.48 ± 17.61 mm<sup>3</sup>/m<sup>2</sup>, <i>p</i> < 0.0001). Increased EAT volumes located around the LA (EAT-LA) were correlated with recurrence (25.55 ± 6.37 vs. 15.54 ± 8.44, <i>p</i> < 0.0001). Conclusions: RCA stenosis, together with atrial volumes and EAT-AS evaluated by CCTA, is associated with the risk of AF recurrence following PVI.https://www.mdpi.com/2075-1729/13/9/1891atrial fibrillationpredictors for AF recurrenceleft atrium diametercalcium scoreleft atrial volume index |
| spellingShingle | Lehel László Bordi Theodora Benedek István Kovács Diana Opincariu Emese Márton Zsolt Parajkó Renáta Gerculy Imre Benedek Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study Life atrial fibrillation predictors for AF recurrence left atrium diameter calcium score left atrial volume index |
| title | Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study |
| title_full | Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study |
| title_fullStr | Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study |
| title_full_unstemmed | Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study |
| title_short | Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study |
| title_sort | association of atrial fibrillation recurrence with right coronary atherosclerosis and increased left arterial epicardial fat following catheter ablation results of a multimodality study |
| topic | atrial fibrillation predictors for AF recurrence left atrium diameter calcium score left atrial volume index |
| url | https://www.mdpi.com/2075-1729/13/9/1891 |
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