Predictive Factors of Piperacillin Exposure and the Impact on Target Attainment after Continuous Infusion Administration to Critically Ill Patients

Predictive Factors of Piperacillin Exposure and the Impact on Target Attainment after Continuous Infusion Administration to Critically Ill Patients

Critically ill patients undergo significant pathophysiological changes that affect antibiotic pharmacokinetics. Piperacillin/tazobactam administered by continuous infusion (CI) improves pharmacokinetic/pharmacodynamic (PK/PD) target attainment. This study aimed to characterize piperacillin PK after...

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書目詳細資料
Main Authors: Javier Martínez-Casanova, Erika Esteve-Pitarch, Helena Colom-Codina, Víctor Daniel Gumucio-Sanguino, Sara Cobo-Sacristán, Evelyn Shaw, Kristel Maisterra-Santos, Joan Sabater-Riera, Xosé L. Pérez-Fernandez, Raül Rigo-Bonnin, Fe Tubau-Quintano, Jordi Carratalà, Ariadna Padullés-Zamora
格式: Article
語言:English
出版: MDPI AG 2023-03-01
叢編:Antibiotics
主題:
beta-lactam antibiotic
piperacillin
critically ill
continuous infusion
creatinine clearance
population pharmacokinetic approach
在線閱讀:https://www.mdpi.com/2079-6382/12/3/531

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https://www.mdpi.com/2079-6382/12/3/531

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