Mathematical modeling identifies LAG3 and HAVCR2 as biomarkers of T cell exhaustion in melanoma
Summary: Cytotoxic T lymphocytes (CTLs) control tumors via lysis of antigen-presenting targets or through secretion of cytokines such as interferon-γ (IFNG), which inhibit tumor cell proliferation. Improved understanding of CTL interactions within solid tumors will aid the development of immunothera...
| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artikel |
| Språk: | English |
| Publicerad: |
Elsevier
2023-05-01
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| Serie: | iScience |
| Ämnen: | |
| Länkar: | http://www.sciencedirect.com/science/article/pii/S2589004223007435 |